E9EM69 · SHO1_METRA

Function

function

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. Affects fungal virulence.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Biological Processregulation of actin filament polymerization

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    High osmolarity signaling protein MOS1
  • Alternative names
    • Osmosensor MOS1

Gene names

    • Name
      MOS1
    • Synonyms
      SHO1
    • ORF names
      MAA_01571

Organism names

Accessions

  • Primary accession
    E9EM69
  • Secondary accessions
    • A7XZS8

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-23Cytoplasmic
Transmembrane24-44Helical
Topological domain45-67Extracellular
Transmembrane68-88Helical
Topological domain89-96Cytoplasmic
Transmembrane97-117Helical
Topological domain118-126Extracellular
Transmembrane127-147Helical
Topological domain148-306Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004103831-306High osmolarity signaling protein MOS1

Expression

Induction

Expression is up-regulated in insect hemolymph or in artificial media with high osmolarity. Also induced by heat (37 gegrees Celsius) and oxidative stress.

Interaction

Subunit

Forms homooligomers.

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias204-238Polar residues
Region204-242Disordered
Domain246-306SH3

Sequence similarities

Belongs to the SHO1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    33,046
  • Last updated
    2011-04-05 v1
  • Checksum
    40D26B3302A3CFE9
MEHSRPYGGRKRMSLGNILGDPFALATISISLLAWFITFISCVIAQVQANKNKGLPDKDNPDGNFPPFAWWAVVYSLFLIVGVVIVVASDAIQTYHVAVTGYLAGGMVLVTSGVNSLVYSKNGAREAAAAGFILLSMVVIVWIFYFGSTPSSTPRAFLDSFALSKDSGAMHNQAMNGYGGTGRPETSNSVQPPQMYTSAQLNGFENPSPVGGASQAPTAPTMPTYGNNTMQPNNKSNDEEVLPPIDYPYQAKAIYSYEANPSDANEISFSKHEILDVSDVSGRWWQARRRGTNEIGIAPSNYLILL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias204-238Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU106866
EMBL· GenBank· DDBJ
ABU94675.1
EMBL· GenBank· DDBJ
mRNA
ADNJ02000009
EMBL· GenBank· DDBJ
EFZ04497.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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