E9EIH7 · E9EIH7_METAQ

Function

function

Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 1/3.

GO annotations

AspectTerm
Molecular FunctionL-aminoadipate-semialdehyde dehydrogenase activity
Biological Processlysine biosynthetic process via aminoadipic acid
Biological Processsecondary metabolite biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alpha-aminoadipate reductase
  • EC number
  • Alternative names
    • L-aminoadipate-semialdehyde dehydrogenase

Gene names

    • ORF names
      MAC_09675

Organism names

  • Taxonomic identifier
  • Strain
    • CQMa 102
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium

Accessions

  • Primary accession
    E9EIH7

Proteomes

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain633-712Carrier

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,178
  • Mass (Da)
    129,616
  • Last updated
    2011-04-05 v1
  • Checksum
    27412314518CC693
MRQNFLIPDPTCDLDWGGFRGAIHDIFAANAKRVPNRQCVIETRSSRSPERVFTYRQINQASNQLAHHLIAHGCNVGDVVVIYAYRGVDLVVAYMGALKAGATVSVLDPQYPGERQKVLLGVSRPQFLICIQRAIDEFGHLPSLVSDFITTDLDVKATVPALHLSNNGQLTGGTVKGQDCLAAQAPLMEHDPDVTVGPDSIPTLSYTSGTEGIPKGVQGRHYSLTYYTPWMAERFGLSETDRFTMLSGIAHDPIQRDIFTPLFLGGTLICPPVEVITYGLLAEWMNEHKATVTHLTPALGQILIGGATTQFSSLRRAFFVGDLLTKKDCRKLCDLAPNTRVINLFGSTESQRAVSFFEIPSKAEDPDFLDSLPDIIPVGQGMLNVQLLVVDRQDRNRLCGVGETGELFIRAAGLAEGYRGDDERTKELNRSKFVSNWFVDPAKWIRESEPQDASVGYYKGPRDRLYRTGDLGRMREDGSVECTGRIDTQVKIRGFRIELSEIDISLSQHPYVRDNITVIRRDKNEEQTLVTYFVPETRRWFQHLQSEDDPEVIEQEMTSETMASMLRRFKLLSDDCKKFLAAKVPSYAVPSIFIPLARMPLNPNGKIDKPALPFPDPVDLLSGAERRASSVVANMTDTQKRLAAVWASVLPNRSARMFVPESNFFDEGGHSILAQQMFFRLKSEWKDINLPVSVIFRSQTLHALALEIDRALDPIGLRLDAMPLPGDGESEDESYAADARELLSQLPDRIPQAPTDWDYTATPPTVLLTGATGFLGSYILRELLEGPAKARVIVHIRAGDAAAGLARVESTAAAYGLWSPEWSSMIETVVGDISKPSLGVSEDTWKRLSNSVDLIIHNGAHVNWMLPYSSLRATNVISTLDCIRLCTEGKPKRLCFVSSTSTLDTNHYVQLSRDLKTGVLETDDLQGSRKGLGTGYGQSKWASEYIIRNAGARGLTGAIVRPGYITGDPASGISVTDDFLVRLWKGCLQVGARPDINNTLNAVPVSRVSRIVVAAGLLLPTVTGQSLSVAQVTSHPRLKLNEWIGAMELYGYRTPLVPYRDWCAKVVEYVEDEANEEHALLPLFHFVTGDLPANTIAPEMDDSQATAALELYDKRTSSGAPGGPQAVDIGTIGMYLAYLVAVGFLPAPVQKGEQELPEVDVSRLQAVKDALGGRSAKS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL698641
EMBL· GenBank· DDBJ
EFY84267.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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