E9E2G9 · E9E2G9_METAQ

Function

Catalytic activity

  • pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
    EC:4.6.1.16 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

156150100150200250300350400450500550
TypeIDPosition(s)Description
Active site464
Active site472
Active site515

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponenttRNA-intron endonuclease complex
Molecular Functionnucleic acid binding
Molecular FunctiontRNA-intron endonuclease activity
Biological ProcesstRNA-type intron splice site recognition and cleavage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-intron lyase
  • EC number
  • Alternative names
    • tRNA-intron endonuclease Sen2

Gene names

    • ORF names
      MAC_04067

Organism names

  • Taxonomic identifier
  • Strain
    • CQMa 102
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium

Accessions

  • Primary accession
    E9E2G9

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-33Disordered
Compositional bias10-28Polar residues
Region277-358Disordered
Compositional bias299-313Basic and acidic residues
Compositional bias314-328Polar residues
Domain434-523tRNA intron endonuclease catalytic

Sequence similarities

Belongs to the tRNA-intron endonuclease family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    561
  • Mass (Da)
    61,917
  • Last updated
    2011-04-05 v1
  • Checksum
    EA4BFDBF68341965
MAEIQQPPKEDGQVTASPAQASTKSADSRKRGPSVHQIYALPAPIRTFPLPAFYPNNPLSFFAVAYAWLRQVFAPPPAEPTAVHQGVWSKKTFSVHVTDEKSMRALWEQGFYGKGSLSRSEPNWLKREQVRRGMQKTHVSEILTVQRREERAQAKWERARLEQESIRQTRLKEAQQAEADSQSKTATLLPSPSPVAFAAPTGPLELLSLPNSAAEASKKPELVSDTVIAVRAAMEAVMIPLPVDIAPPSILETGNGIVDTNVVSTASFVAGSPQVRGQSSGIGVIETPHPPASETSSDSAEDKTLKRQKSVRFSPKVESTTFNLADPPSPHHSLNGKGKRLLNGALNGPGTAEEAKKLSAEESEDVIVNREHLQLMPEEAFFLTFGFGALSVTDPASGKSLTAKEMLTLFRQYSYFPPRTGGPDESDLGPDDGFLVHYAVYHHFRSLGWVPRAGIKFGVDWLLYTRGPVFDHAEFGLIIVPSYSDAWWKDRGKQGPQKTWAWLHSVIRVLSHVIKSLVLVYVDIPPPPKFDAALETGFAEALHLYRVREVMVKRWSSNRNR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias10-28Polar residues
Compositional bias299-313Basic and acidic residues
Compositional bias314-328Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL698495
EMBL· GenBank· DDBJ
EFY89858.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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