Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum.
- AnnotationMutations in SERCA disrupt Wingless signaling by sequestering Armadillo/beta-catenin away from the signaling pool. Elimination of SERCA function results in apoptosis.
- CategoryFunction
- SourceGeneRif: 49297