E7RT80 · E7RT80_9BACT
- ProteinNa(+)-translocating NADH-quinone reductase subunit C
- GenenqrC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids241 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Catalytic activity
- a ubiquinone + H+ + n Na+(in) + NADH = a ubiquinol + n Na+(out) + NAD+
a ubiquinone RHEA-COMP:9565 + CHEBI:15378 + n Na+ (in)CHEBI:29101+ CHEBI:57945 = a ubiquinol RHEA-COMP:9566 + n Na+ (out)CHEBI:29101+ CHEBI:57540
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | FMN binding | |
Molecular Function | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNa(+)-translocating NADH-quinone reductase subunit C
- EC number
- Short namesNa(+)-NQR subunit C ; Na(+)-translocating NQR subunit C
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Prevotellaceae > Hoylesella
Accessions
- Primary accessionE7RT80
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 18-39 | Helical | ||||
Sequence: IIYSAFVVIVVAFLLAFVFQAL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 217 | FMN phosphoryl threonine | ||||
Sequence: T |
Keywords
- PTM
Interaction
Subunit
Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 135-234 | FMN-binding | ||||
Sequence: GLWGAISGYIAINDDKSTVFGAYFNHESETAGLGAEIKDNQKWQEKFQGKKLFLNDKSSSIALSVNKKVSDPKTQVDAITGATLTSNGVTEMLHDCIGQY |
Sequence similarities
Belongs to the NqrC family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length241
- Mass (Da)26,117
- Last updated2011-04-05 v1
- Checksum3CFC7B72D387ABB6
Keywords
- Technical term