E7RS29 · E7RS29_9BACT
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids733 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- Na+(in) + diphosphate + H2O = Na+(out) + 2 phosphate + H+Na+ (in)CHEBI:29101
+ CHEBI:33019 + CHEBI:15377 = Na+ (out)CHEBI:29101+ 2 CHEBI:43474 + CHEBI:15378
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 484 | Determinant of potassium dependence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Prevotellaceae > Hoylesella
Accessions
- Primary accessionE7RS29
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-29 | Helical | |||
Transmembrane | 59-78 | Helical | |||
Transmembrane | 84-107 | Helical | |||
Transmembrane | 128-154 | Helical | |||
Transmembrane | 166-186 | Helical | |||
Transmembrane | 270-292 | Helical | |||
Transmembrane | 304-329 | Helical | |||
Transmembrane | 336-355 | Helical | |||
Transmembrane | 389-413 | Helical | |||
Transmembrane | 425-445 | Helical | |||
Transmembrane | 489-507 | Helical | |||
Transmembrane | 555-577 | Helical | |||
Transmembrane | 627-646 | Helical | |||
Transmembrane | 653-670 | Helical | |||
Transmembrane | 713-732 | Helical | |||
Keywords
- Cellular component
Interaction
Structure
Sequence
- Sequence statusComplete
- Length733
- Mass (Da)76,775
- Last updated2011-04-05 v1
- Checksum96227618648D67DB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AEPE02000006 EMBL· GenBank· DDBJ | EFZ36030.1 EMBL· GenBank· DDBJ | Genomic DNA |