E7F9V1 · E7F9V1_DANRE

Function

function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentacetylcholine-gated channel complex
Cellular Componentneuron projection
Cellular Componentplasma membrane
Cellular Componentpostsynaptic membrane
Cellular Componentsynapse
Molecular Functionacetylcholine-gated monoatomic cation-selective channel activity
Molecular Functiontransmembrane signaling receptor activity
Biological Processacetylcholine receptor signaling pathway
Biological Processcellular response to acetylcholine
Biological Processmembrane depolarization
Biological Processsynaptic transmission, cholinergic

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Acetylcholine receptor subunit gamma

Gene names

    • Name
      chrng
    • Synonyms
      chrngl
      , wu:fc54e06

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    E7F9V1
  • Secondary accessions
    • A0A8M1NYX6

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein
Postsynaptic cell membrane
; Multi-pass membrane protein
Synaptic cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane247-270Helical
Transmembrane282-301Helical
Transmembrane313-336Helical
Transmembrane492-514Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_503503529725-540Acetylcholine receptor subunit gamma

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain29-246Neurotransmitter-gated ion-channel ligand-binding
Domain253-509Neurotransmitter-gated ion-channel transmembrane
Region521-540Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    540
  • Mass (Da)
    62,145
  • Last updated
    2011-03-08 v1
  • Checksum
    71FC341F158642F5
MDQNLSSKIIWLWILLFRFSGALCNLEGSLHRDLMVGYNKNIRPVESHEDIIDVKIKMTLTNLISLNEKEETLTTCVWIEMQWRDYRLRWANRTGFEVYENITRMRLPSKTIWLPDIGLENNVDGRFEVALYANTLIDPDGSVYWLPPAIYRSSCAIKVNYFPFDWQNCSMVFRSQTYNSNEITLMLSDEDNVTMEWIEIDPEAFTENGEWMIKHRPAKKVINKRYRPDELEHQEIIFFLIIQRKPLFYVINIIVPCVLFSSLGLLVYFLPAKAGGQKCTMTICILLGQTVFLFLIAKKVPETSQAVPLIGKYLMFVMSVTTITVMNCVVVLNVSLRTPNTHPMSNTIRKVLLNILPRVLRMTMQRWTPEQEEGDFKMFALGNGTPLRRRRRSSLGLIAKADEYMFRTARSELMFSRLKERKGLLKNTLEKIQNGLGGNTAQDLECSLAAASPEVQQCVSSCKHIAESTKHQNDFQSKNEEWFLVARVIDRMCFFVMALLFILGTIGIFLTGHFNQAPSQPFPGDPKKYLPEISAGDIPG

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
G1FMP9G1FMP9_DANREchrng540

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR293505
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CU929150
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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