E7EX57 · E7EX57_HUMAN

  • Protein
    Multidrug and toxin extrusion protein 1
  • Gene
    SLC47A1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Molecular Functionantiporter activity
Molecular Functionxenobiotic transmembrane transporter activity
Biological Processxenobiotic detoxification by transmembrane export across the plasma membrane

Names & Taxonomy

Protein names

  • Recommended name
    Multidrug and toxin extrusion protein 1
  • Alternative names
    • Solute carrier family 47 member 1

Gene names

    • Name
      SLC47A1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    E7EX57

Proteomes

Organism-specific databases

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane37-62Helical
Transmembrane97-121Helical
Transmembrane133-150Helical
Transmembrane162-182Helical
Transmembrane194-213Helical
Transmembrane233-253Helical
Transmembrane274-295Helical
Transmembrane315-334Helical
Transmembrane355-376Helical
Transmembrane391-413Helical

Keywords

  • Cellular component

Disease & Variants

Variants

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The viewer provides 558 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)23PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    443
  • Mass (Da)
    48,027
  • Last updated
    2011-03-08 v1
  • Checksum
    5255E025EFD592F2
MEAPEEPAPVRGGPEATLEVRGSRCLRLSAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIATYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGSGTRQFESKQRASEWEFCSPSGSASPRVP

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q96FL8S47A1_HUMANSLC47A1570
J3KRZ3J3KRZ3_HUMANSLC47A199
J3KSS8J3KSS8_HUMANSLC47A1316
I3L345I3L345_HUMANSLC47A1268

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC004448
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC025627
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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