E7EWN5 · E7EWN5_HUMAN

  • Protein
    BRCA1 DNA repair associated
  • Gene
    BRCA1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionmetal ion binding
Biological ProcessDNA repair

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • BRCA1 DNA repair associated

Gene names

    • Name
      BRCA1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    E7EWN5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)114PRIDEPhosphoserine
Modified residue (large scale data)377PRIDEPhosphoserine
Modified residue (large scale data)378PRIDEPhosphoserine
Modified residue (large scale data)395PRIDEPhosphoserine
Modified residue (large scale data)398PRIDEPhosphoserine
Modified residue (large scale data)403PRIDEPhosphoserine
Modified residue (large scale data)422PRIDEPhosphotyrosine
Modified residue (large scale data)426PRIDEPhosphoserine
Modified residue (large scale data)434PRIDEPhosphoserine
Modified residue (large scale data)451PRIDEPhosphoserine
Modified residue (large scale data)454PRIDEPhosphoserine
Modified residue (large scale data)509PRIDEPhosphothreonine
Modified residue (large scale data)510PRIDEPhosphoserine
Modified residue (large scale data)551PRIDEPhosphoserine

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain24-65RING-type
Compositional bias230-248Polar residues
Region230-270Disordered
Region306-338Disordered
Compositional bias324-338Basic and acidic residues
Compositional bias534-569Polar residues
Region534-570Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    649
  • Mass (Da)
    73,088
  • Last updated
    2011-03-08 v1
  • MD5 Checksum
    5E13499E04A5B324FC4F038579EE122F
MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEE

Computationally mapped potential isoform sequences

There are 20 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P38398BRCA1_HUMANBRCA11863
C9IZW4C9IZW4_HUMANBRCA11567
G1UI37G1UI37_HUMANBRCA123
A0A2R8Y7V5A0A2R8Y7V5_HUMANBRCA11885
A0A2R8Y6Y9A0A2R8Y6Y9_HUMANBRCA181
A0A0U1RRA9A0A0U1RRA9_HUMANBRCA11822
E7EUM2E7EUM2_HUMANBRCA1759
E7EQW4E7EQW4_HUMANBRCA11861
E9PC22E9PC22_HUMANBRCA159
Q3B891Q3B891_HUMANBRCA1473
H0Y8D8H0Y8D8_HUMANBRCA11821
H0Y8B8H0Y8B8_HUMANBRCA1717
H0Y850H0Y850_HUMANBRCA11862
A0A9Y1QPT7A0A9Y1QPT7_HUMANBRCA1713
A0A8V8TPY7A0A8V8TPY7_HUMANBRCA1544
C6YB45C6YB45_HUMANBRCA1173
A0A494C182A0A494C182_HUMANBRCA1601
K7EJW3K7EJW3_HUMANBRCA196
E7ENB7E7ENB7_HUMANBRCA11837
K7EPC7K7EPC7_HUMANBRCA1354

Features

Showing features for compositional bias, non-terminal residue.

Type
IDPosition(s)Description
Compositional bias230-248Polar residues
Compositional bias324-338Basic and acidic residues
Compositional bias534-569Polar residues
Non-terminal residue649

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC060780
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC135721
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KF456281
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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