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E7EST5 · E7EST5_HUMAN

  • Protein
    Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
  • Gene
    KIR2DL4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane

Names & Taxonomy

Protein names

  • Submitted names
    • Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4

Gene names

    • Name
      KIR2DL4

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    E7EST5

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane283-301Helical

Keywords

  • Cellular component

Disease & Variants

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)120PRIDEPhosphoserine

Keywords

Expression

Gene expression databases

    • ENSG00000189013Expressed in male germ line stem cell (sensu Vertebrata) in testis and 79 other cell types or tissues

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region13-37Disordered
Domain75-159Immunoglobulin
Domain170-257Immunoglobulin
Region377-416Disordered
Compositional bias392-416Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    416
  • Mass (Da)
    45,439
  • Last updated
    2014-10-29 v2
  • MD5 Checksum
    17F8B7E3ED7091764B5430C581CE673D
MSPSHVVVNVSTARSGPLTTSSAPVSRAESLRPGSRSCTMSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARHLHAVIRYSVAIILFTILPFFLLHRWCSKKKDAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI

Computationally mapped potential isoform sequences

There are 32 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q99706KI2L4_HUMANKIR2DL4377
A8MT18A8MT18_HUMANKIR2DL4398
K7QUT1K7QUT1_HUMANKIR2DL4377
A0A5K1U1N8A0A5K1U1N8_HUMANKIR2DL4358
K7RE46K7RE46_HUMANKIR2DL4273
A0A1W2PQV0A0A1W2PQV0_HUMANKIR2DL4398
Q86U48Q86U48_HUMANKIR2DL4377
A0A0C4ZNX8A0A0C4ZNX8_HUMANKIR2DL4377
A0A0G2JP28A0A0G2JP28_HUMANKIR2DL4273
A0A0G2JNZ6A0A0G2JNZ6_HUMANKIR2DL4325
A0A0G2JQ13A0A0G2JQ13_HUMANKIR2DL4230
A0A0G2JPN7A0A0G2JPN7_HUMANKIR2DL4325
A0A0G2JPS9A0A0G2JPS9_HUMANKIR2DL4342
A0A0G2JQ39A0A0G2JQ39_HUMANKIR2DL4256
A0A0G2JPE3A0A0G2JPE3_HUMANKIR2DL4342
A0A0G2JPG6A0A0G2JPG6_HUMANKIR2DL4416
A0A0G2JMF5A0A0G2JMF5_HUMANKIR2DL4312
A0A0G2JMD1A0A0G2JMD1_HUMANKIR2DL4399
A0A0G2JMQ9A0A0G2JMQ9_HUMANKIR2DL4325
A0A0G2JLZ7A0A0G2JLZ7_HUMANKIR2DL4246
A0A0G2JNK6A0A0G2JNK6_HUMANKIR2DL4312
A0A0G2JNE8A0A0G2JNE8_HUMANKIR2DL4342
A0A0G2JNG7A0A0G2JNG7_HUMANKIR2DL4310
A0A0G2JNI1A0A0G2JNI1_HUMANKIR2DL4399
A0A0G2JMV5A0A0G2JMV5_HUMANKIR2DL4360
A0A0G2JN69A0A0G2JN69_HUMANKIR2DL4416
Q8N736Q8N736_HUMANKIR2DL4247
A0A0B4J1S6A0A0B4J1S6_HUMANKIR2DL4273
A0A5K1V8C4A0A5K1V8C4_HUMANKIR2DL4358
A0A0G2JLN0A0A0G2JLN0_HUMANKIR2DL4245
A0A0G2JLM0A0A0G2JLM0_HUMANKIR2DL4312
A0A0G2JLM4A0A0G2JLM4_HUMANKIR2DL4245

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias392-416Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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