E7CWU1 · E7CWU1_SIV

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

AspectTerm
Cellular Componenthost cell endosome membrane
Cellular Componenthost cell plasma membrane
Cellular Componentplasma membrane
Cellular Componentviral envelope
Cellular Componentvirion membrane
Molecular Functionstructural molecule activity
Biological Processapoptotic process
Biological Processmembrane fusion involved in viral entry into host cell
Biological Processsymbiont entry into host cell
Biological Processvirion attachment to host cell

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Envelope glycoprotein gp160
  • Cleaved into 2 chains

Gene names

    • Name
      env

Organism names

Accessions

  • Primary accession
    E7CWU1

Subcellular Location

Host cell membrane
; Peripheral membrane protein
Host cell membrane
; Single-pass type I membrane protein
Host endosome membrane
; Peripheral membrane protein
Host endosome membrane
; Single-pass type I membrane protein
Virion membrane
; Peripheral membrane protein
Virion membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-32Helical
Transmembrane527-548Helical
Transmembrane690-711Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. The resulting complex protrudes from the virus surface as a spike.

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain24-525Human immunodeficiency virus 1 envelope glycoprotein Gp120
Domain543-738Retroviral envelope protein GP41-like
Coiled coil637-664

Domain

The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    879
  • Mass (Da)
    100,875
  • Last updated
    2011-03-08 v1
  • Checksum
    2ED923B3D28A7413
MGCLGNQLLIAILLLSVYGIYCTLYVTVFYGVPAWRNATIPLFCATKNRDTWGTTQCLPDNGDYSEMALNVTESFDAWNNTVTEQAIEDVWQLFETSIKPCVKLSPLCITMRCNKSETDRWGLTKSITTTASTTSTTASAKVDMVNETSSCIAQDNCAGLEQEQMISCKFNMTGLKRDKKKEYNETWYSTDLVCEQGNNTGNESRCYMNHCNTSVIQESCDKHYWDAIRFRYCAPPGYALLRCNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPINDRPKQAWCWFGGEWKDAIKEVKQTIVKHPRYTGTNDTGKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRNTTNQKPREQYKRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWIHGNQTNITMSAEVAELYRLELGDYKLVEITPIGLAPTGVKRYTTGGTSRNKRGVFVLGFLGFLATAGSAMGAASLTLTAQSRTLLAGIVRQQQQLLDVVKRQQELLRLTVWGTKNLQTRVTAIEKYLKDQAQLNAWGCAFRQVCHTTVPWPNASLTPKWNNETWQEWERKVDFLEENITALLEEAQIQQEKNMYELQKLNSWDVFGNWFDLASWIKYIQYGVYIVVGVILLRIVIYIVQMLAKLRQGYRPVFSSPPSYFQQTHIQQDPALPTREGKGGDGGEGGGNSSWPWQIEYIHFLIRQLIRLLTWLFSNCRTLLSRVYQILQPIFQRLSATLQRIREVLRTELTYLQYGWSYFHEAVQAVWRSATETLAGAWGDLWETLRRGGRWILAVPRRIRQGLELTLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM800206
EMBL· GenBank· DDBJ
ADV17146.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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