E7BTI3 · E7BTI3_BOSIN
- ProteinATP synthase protein 8
- GeneATP8
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial membrane | |
Cellular Component | proton-transporting ATP synthase complex, coupling factor F(o) | |
Molecular Function | proton transmembrane transporter activity | |
Biological Process | proton motive force-driven ATP synthesis |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameATP synthase protein 8
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionE7BTI3
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-24 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ. Interacts with PRICKLE3.
Structure
Sequence
- Sequence statusComplete
- Length66
- Mass (Da)7,921
- Last updated2011-03-08 v1
- MD5 Checksum4B27B4678CC07D37AAD094A0BBC59CF4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GU256940 EMBL· GenBank· DDBJ | ACZ83015.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087789 EMBL· GenBank· DDBJ | AER39271.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087790 EMBL· GenBank· DDBJ | AER39273.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087791 EMBL· GenBank· DDBJ | AER39275.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087792 EMBL· GenBank· DDBJ | AER39277.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087793 EMBL· GenBank· DDBJ | AER39279.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087794 EMBL· GenBank· DDBJ | AER39281.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087795 EMBL· GenBank· DDBJ | AER39283.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087796 EMBL· GenBank· DDBJ | AER39285.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087797 EMBL· GenBank· DDBJ | AER39287.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087798 EMBL· GenBank· DDBJ | AER39289.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087799 EMBL· GenBank· DDBJ | AER39291.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087800 EMBL· GenBank· DDBJ | AER39293.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087801 EMBL· GenBank· DDBJ | AER39295.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087802 EMBL· GenBank· DDBJ | AER39297.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087803 EMBL· GenBank· DDBJ | AER39299.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087804 EMBL· GenBank· DDBJ | AER39301.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087805 EMBL· GenBank· DDBJ | AER39303.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087806 EMBL· GenBank· DDBJ | AER39305.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087807 EMBL· GenBank· DDBJ | AER39307.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087808 EMBL· GenBank· DDBJ | AER39309.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087809 EMBL· GenBank· DDBJ | AER39311.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087810 EMBL· GenBank· DDBJ | AER39313.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087811 EMBL· GenBank· DDBJ | AER39315.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087812 EMBL· GenBank· DDBJ | AER39317.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087813 EMBL· GenBank· DDBJ | AER39319.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087814 EMBL· GenBank· DDBJ | AER39321.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087815 EMBL· GenBank· DDBJ | AER39323.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087816 EMBL· GenBank· DDBJ | AER39325.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087817 EMBL· GenBank· DDBJ | AER39327.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087818 EMBL· GenBank· DDBJ | AER39329.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087819 EMBL· GenBank· DDBJ | AER39331.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087820 EMBL· GenBank· DDBJ | AER39333.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087821 EMBL· GenBank· DDBJ | AER39335.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087822 EMBL· GenBank· DDBJ | AER39337.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087823 EMBL· GenBank· DDBJ | AER39339.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087824 EMBL· GenBank· DDBJ | AER39341.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087825 EMBL· GenBank· DDBJ | AER39343.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087826 EMBL· GenBank· DDBJ | AER39345.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087827 EMBL· GenBank· DDBJ | AER39347.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087828 EMBL· GenBank· DDBJ | AER39349.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087829 EMBL· GenBank· DDBJ | AER39351.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087830 EMBL· GenBank· DDBJ | AER39353.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087831 EMBL· GenBank· DDBJ | AER39355.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087832 EMBL· GenBank· DDBJ | AER39357.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087833 EMBL· GenBank· DDBJ | AER39359.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087834 EMBL· GenBank· DDBJ | AER39361.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087835 EMBL· GenBank· DDBJ | AER39363.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087836 EMBL· GenBank· DDBJ | AER39365.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087837 EMBL· GenBank· DDBJ | AER39367.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087838 EMBL· GenBank· DDBJ | AER39369.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087839 EMBL· GenBank· DDBJ | AER39371.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087840 EMBL· GenBank· DDBJ | AER39373.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087841 EMBL· GenBank· DDBJ | AER39375.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087842 EMBL· GenBank· DDBJ | AER39377.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087843 EMBL· GenBank· DDBJ | AER39379.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087844 EMBL· GenBank· DDBJ | AER39381.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087845 EMBL· GenBank· DDBJ | AER39383.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087846 EMBL· GenBank· DDBJ | AER39385.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087847 EMBL· GenBank· DDBJ | AER39387.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087848 EMBL· GenBank· DDBJ | AER39389.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087849 EMBL· GenBank· DDBJ | AER39391.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087850 EMBL· GenBank· DDBJ | AER39393.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087851 EMBL· GenBank· DDBJ | AER39395.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087852 EMBL· GenBank· DDBJ | AER39397.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087853 EMBL· GenBank· DDBJ | AER39399.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JN087854 EMBL· GenBank· DDBJ | AER39401.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KX575711 EMBL· GenBank· DDBJ | APW83416.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
KX759625 EMBL· GenBank· DDBJ | ARF05611.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MF667929 EMBL· GenBank· DDBJ | ATV96238.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MF667930 EMBL· GenBank· DDBJ | ATV96251.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MF667931 EMBL· GenBank· DDBJ | ATV96264.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MF667932 EMBL· GenBank· DDBJ | ATV96277.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK335920 EMBL· GenBank· DDBJ | QIC19674.1 EMBL· GenBank· DDBJ | Genomic DNA |