E7BMD2 · E7BMD2_9GAMM

  • Protein
    Peptidyl-prolyl cis-trans isomerase
  • Gene
    mip
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell outer membrane
Molecular Functionpeptidyl-prolyl cis-trans isomerase activity
Biological Processprotein folding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptidyl-prolyl cis-trans isomerase
  • EC number

Gene names

    • Name
      mip

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ST7319
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Legionellales > Legionellaceae > Legionella

Accessions

  • Primary accession
    E7BMD2

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_500321596221-214Peptidyl-prolyl cis-trans isomerase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain144-214PPIase FKBP-type

Sequence similarities

Belongs to the FKBP-type PPIase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    214
  • Mass (Da)
    22,839
  • Last updated
    2011-03-08 v1
  • Checksum
    89E3BFB4B4A2A08E
MKMRLVTGALMGLAMSTVMAATDATSLVTDKDKLSYSIGADLGKNFKNQGIDINPDALAKGMQDGMSGAQLILTEQQMKDVLNKFQKELMAKRSAEFNKKAEENKSKGDAFLSTNKSKSGVTVLPSGLQYKVIEAGTGNKPGKSDTVTVEYTGTLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVPSDLAYGPRSVGGPR

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue214

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GU083705
EMBL· GenBank· DDBJ
ADR82221.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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