E6WVH7 · E6WVH7_PSEUU

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionribonucleoside binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta
  • EC number
  • Short names
    RNAP subunit beta
  • Alternative names
    • RNA polymerase subunit beta
    • Transcriptase subunit beta

Gene names

    • Name
      rpoB
    • Ordered locus names
      Psesu_2342

Organism names

Accessions

  • Primary accession
    E6WVH7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain28-527RNA polymerase beta subunit protrusion
Domain156-230RNA polymerase Rpb2
Domain362-418RNA polymerase Rpb2
Domain541-608RNA polymerase Rpb2
Domain619-684DNA-directed RNA polymerase beta subunit external 1
Domain746-1318DNA-directed RNA polymerase subunit 2 hybrid-binding
Domain1320-1395RNA polymerase Rpb2

Sequence similarities

Belongs to the RNA polymerase beta chain family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,396
  • Mass (Da)
    155,769
  • Last updated
    2011-03-08 v1
  • Checksum
    CE4D11BA8075A013
MTTYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYRDFLQADTDSAKRRDTGLHAALKSVFPIASYSGNAALEYVGYKLGEPVFDERECRNRGLSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTEHGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALYTRIDRRRKLPVTILLRALGYNNEEMLRAFFEINTFHIDPSEGVQLELVPERLRGETLGFDLADGEKVIVEAGKRITARHVRQLEQSGITALAVPDEYLLGRILAHDVVDAATGELLAAANDEITDEHLAAFRKAGVASVGTLWVNDLDRGPYLSNTLRIDPSRTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSAVGRMKFNRRVGRKDVLGPAVLFDHKYFSERNDEDSKALVAAQGETSDILDVLRVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVVDGRITDQVEYLSAIEENEYVIAQVNAAHDKEGRLTEAFVPVRHQGESLLKPPGEIHYMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRAQTPLVGTGIERAVARDSGVTVNARRGGEVVQVDAGRIVVKANEEEISGEHDAGVDIYTLTKYTRSNQNTCINQRPLVHVGDVVARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVQEDRYTTIHIEELTCVARDTKLGPEEITADIPNVSEQALNRLDESGVVYIGAEVRAGDILVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRAKQIEENEIRRVKKDFDDQFRILEAAIYARLRGQIVGKVANGGPGLKKGDAITDAYLDGLKKADWFLLRMKDEEASDAIERAQKQIAAHEKEFERRFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMADGTPVDICLNPLGVPSRMNIGQILEVHLGWAAKGLGKRIQKMLDEQRAVSELREFLDKVYNHDSSLVGQRVDLSQFSDEELLGMARNLTGGVPMATPVFDGAYEDEIRQMLELAYPTDDPETVRLGFNATKTQMQLHDGRTGEAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGNHEMVAGMPESFNVLVKEIRSLAINMELEDE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002446
EMBL· GenBank· DDBJ
ADV28176.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help