E6KWD8 · E6KWD8_9PAST

Function

function

Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site9substrate
Binding site26substrate
Binding site37substrate
Binding site46substrate
Binding site50substrate
Binding site84substrate
Binding site88substrate
Site278Essential for prephenate dehydratase activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionchorismate mutase activity
Molecular Functionprephenate dehydratase activity
Biological Processchorismate metabolic process
Biological ProcessL-phenylalanine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional chorismate mutase/prephenate dehydratase
  • EC number
  • Alternative names
    • Chorismate mutase-prephenate dehydratase
    • p-protein

Gene names

    • Name
      pheA
    • ORF names
      HMPREF9064_0482

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 33393
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pasteurellales > Pasteurellaceae > Aggregatibacter

Accessions

  • Primary accession
    E6KWD8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-92Chorismate mutase
Domain105-285Prephenate dehydratase
Domain299-376ACT

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    387
  • Mass (Da)
    44,178
  • Last updated
    2011-03-08 v1
  • Checksum
    27D6A1AE0325BCF1
MSLDLSEIRQQITQIDRSLLKLLSERHRLAFDVVRSKELTQKPLRDAEREEQLLQELVQFAENENYQLEPQYITSIFQKIIEDSVLTQQVYLQKKLNAQREQNIHIAFLGKRGSYSHLAARNYATRYQEELVEISCASFDEVFAKVQHGEADYGVLPLENTTSGAINEVYDLLQHTDLFLVGELAYPIQHCVLVNGQDDLSKIDTLYSHPQVIQQCSHFIHGLERVHIEYCESSSHAMQLVAGLNKPNIAALGNEDGGKLYGLNVLKRNVANQENNITRFIVIAKKPHSVSPQIHTKTLLLMSTGQQAGALVDALLVFKKHHINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTQSALEELKQFSHYLKILGCYPSEIVKPTALPK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEPS01000003
EMBL· GenBank· DDBJ
EFU67819.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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