E5RFS5 · E5RFS5_HUMAN

  • Protein
    FYN proto-oncogene, Src family tyrosine kinase
  • Gene
    FYN
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentplasma membrane

Names & Taxonomy

Subcellular Location

Disease & Variants

Variants

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The viewer provides 147 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)21PRIDEPhosphoserine
Modified residue (large scale data)25PRIDEPhosphoserine
Modified residue (large scale data)26PRIDEPhosphoserine
Modified residue (large scale data)28PRIDEPhosphotyrosine
Modified residue (large scale data)185PRIDEPhosphotyrosine
Modified residue (large scale data)186PRIDEPhosphoserine
Modified residue (large scale data)213PRIDEPhosphotyrosine
Modified residue (large scale data)214PRIDEPhosphotyrosine

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region14-35Disordered
Compositional bias18-35Polar residues
Domain82-143SH3
Domain149-232SH2

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    232
  • Mass (Da)
    26,044
  • Last updated
    2011-02-08 v1
  • Checksum
    7019722AC49FF058
MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYS

Computationally mapped potential isoform sequences

There are 13 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P06241FYN_HUMANFYN537
E5RHX7E5RHX7_HUMANFYN70
E5RIX5E5RIX5_HUMANFYN186
E5RK23E5RK23_HUMANFYN106
E5RJX7E5RJX7_HUMANFYN64
E5RGT0E5RGT0_HUMANFYN153
E5RGM6E5RGM6_HUMANFYN139
E5RH71E5RH71_HUMANFYN175
E5RHF7E5RHF7_HUMANFYN118
E5RI25E5RI25_HUMANFYN145
E5RFM0E5RFM0_HUMANFYN152
E5RFM4E5RFM4_HUMANFYN116
E5RFM6E5RFM6_HUMANFYN103

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias18-35Polar residues
Non-terminal residue232

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL109916
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL158035
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
Z97989
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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