E5R540 · KEX1_LEPMJ

Function

function

Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).

Catalytic activity

  • Preferential release of a C-terminal arginine or lysine residue.
    EC:3.4.16.6 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

164150100150200250300350400450500550600
TypeIDPosition(s)Description
Active site182
Active site382
Active site444

GO annotations

AspectTerm
Cellular ComponentGolgi apparatus
Cellular Componentmembrane
Molecular Functionserine-type carboxypeptidase activity
Biological Processapoptotic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Pheromone-processing carboxypeptidase KEX1
  • EC number
  • Alternative names
    • Carboxypeptidase D

Gene names

    • Name
      KEX1
    • ORF names
      Lema_P047160

Organism names

Accessions

  • Primary accession
    E5R540

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain36-515Lumenal
Transmembrane516-536Helical
Topological domain537-641Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-35
ChainPRO_000041192336-641Pheromone-processing carboxypeptidase KEX1
Glycosylation118N-linked (GlcNAc...) asparagine
Glycosylation433N-linked (GlcNAc...) asparagine
Glycosylation441N-linked (GlcNAc...) asparagine
Glycosylation493N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region472-502Disordered
Region585-641Disordered

Sequence similarities

Belongs to the peptidase S10 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    641
  • Mass (Da)
    72,004
  • Last updated
    2011-02-08 v1
  • Checksum
    EBC87398725E1F59
MASTYSTPRWRTALLGGFLTTLPWLSSGMAGKTQADYFIKSLPGAPEPLLKMHAGHIEVDAEHNGNLFFWHYENRHIADRQRTVLWLNGGPGCSSMDGALMEVGPYRVQADGNLHYNNGSWDEFANLLFVDQPVGTGFSYVNTDSYLTELDQMANHMVIFLEKWFGLFPEYEHDDLYIAGESYAGQHIPYIARAIVKRNKEQGKTPWALKGLLIGNGWISPVDQYLSYIPYAYQNGLMKADSDMAKRVENQQRICIKKLEDGGMDAVDTNDCEQIMVNILEETKDRKADRMNQCVNMYDIRLRDDASCGMNWPPDLASVTPYLRRPDVIQALHINPDKKTGWQECNGAVSGHFRAKKSEPSVRFLPELIPEVPTLLFSGDKDFICNHIGTEEMIKNMQWSGGKGFEVTPGVWAPKQDWTFEGEAAGSWQEARNLTYVVFYNSSHMVPFDYPRRTRDMLDRFMGVDIEQIGGVPSDSRIDGEKGPLTSVGDHPNSTRAEEDKATDVKQAEWKAYYRSGQVALVVVVIVAALWGIFLWRSRRRHTKTAYQGDDGDEGRESLLTGMGLDNFRRKERRSDLEAADFDERELDDLDGASKKPGNGYASLGSEKERQSHNDSTFSLGGDSDDEAGSSDGPKRKGGSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FP929083
EMBL· GenBank· DDBJ
CBX92010.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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