E5KMT5 · E5KMT5_HUMAN

  • Protein
    Mitochondrial tRNA pseudouridine synthase A
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Features

Showing features for active site, binding site.

142750100150200250300350400
TypeIDPosition(s)Description
Active site146Nucleophile
Binding site201substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleoplasm
Molecular Functionpseudouridine synthase activity
Molecular FunctionRNA binding
Biological ProcessmRNA pseudouridine synthesis
Biological ProcesstRNA pseudouridine synthesis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Mitochondrial tRNA pseudouridine synthase A

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    E5KMT5

Organism-specific databases

Subcellular Location

Disease & Variants

Organism-specific databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region20-83Disordered
Compositional bias50-83Basic and acidic residues
Domain239-341Pseudouridine synthase I TruA alpha/beta
Region407-427Disordered

Sequence similarities

Belongs to the tRNA pseudouridine synthase TruA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    427
  • Mass (Da)
    47,470
  • Last updated
    2011-02-08 v1
  • Checksum
    ACE9FA6AE0F178BA
MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias50-83Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HQ205066
EMBL· GenBank· DDBJ
ADP90494.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205067
EMBL· GenBank· DDBJ
ADP90496.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205068
EMBL· GenBank· DDBJ
ADP90498.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205069
EMBL· GenBank· DDBJ
ADP90500.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205070
EMBL· GenBank· DDBJ
ADP90502.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205071
EMBL· GenBank· DDBJ
ADP90504.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205072
EMBL· GenBank· DDBJ
ADP90506.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205073
EMBL· GenBank· DDBJ
ADP90508.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205074
EMBL· GenBank· DDBJ
ADP90510.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205075
EMBL· GenBank· DDBJ
ADP90512.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205076
EMBL· GenBank· DDBJ
ADP90514.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205077
EMBL· GenBank· DDBJ
ADP90516.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205078
EMBL· GenBank· DDBJ
ADP90518.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205079
EMBL· GenBank· DDBJ
ADP90520.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205080
EMBL· GenBank· DDBJ
ADP90522.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205081
EMBL· GenBank· DDBJ
ADP90524.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205082
EMBL· GenBank· DDBJ
ADP90526.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205083
EMBL· GenBank· DDBJ
ADP90528.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205084
EMBL· GenBank· DDBJ
ADP90530.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205085
EMBL· GenBank· DDBJ
ADP90532.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205086
EMBL· GenBank· DDBJ
ADP90534.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205087
EMBL· GenBank· DDBJ
ADP90536.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205088
EMBL· GenBank· DDBJ
ADP90538.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205089
EMBL· GenBank· DDBJ
ADP90540.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205090
EMBL· GenBank· DDBJ
ADP90542.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205091
EMBL· GenBank· DDBJ
ADP90544.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205092
EMBL· GenBank· DDBJ
ADP90546.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205093
EMBL· GenBank· DDBJ
ADP90548.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205094
EMBL· GenBank· DDBJ
ADP90550.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205095
EMBL· GenBank· DDBJ
ADP90552.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205096
EMBL· GenBank· DDBJ
ADP90554.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205097
EMBL· GenBank· DDBJ
ADP90556.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205098
EMBL· GenBank· DDBJ
ADP90558.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205099
EMBL· GenBank· DDBJ
ADP90560.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205100
EMBL· GenBank· DDBJ
ADP90562.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205101
EMBL· GenBank· DDBJ
ADP90564.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205102
EMBL· GenBank· DDBJ
ADP90566.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205103
EMBL· GenBank· DDBJ
ADP90568.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205104
EMBL· GenBank· DDBJ
ADP90570.1
EMBL· GenBank· DDBJ
Genomic DNA
HQ205105
EMBL· GenBank· DDBJ
ADP90572.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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