E5FGN1 · E5FGN1_MACFA
- ProteinNibrin
- GeneNBN
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids754 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromosome, telomeric region | |
Cellular Component | Mre11 complex | |
Cellular Component | PML body | |
Biological Process | double-strand break repair | |
Biological Process | meiotic cell cycle | |
Biological Process | mitotic G2 DNA damage checkpoint signaling | |
Biological Process | telomere maintenance |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameNibrin
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Macaca
Accessions
- Primary accessionE5FGN1
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 24-83 | FHA | ||||
Sequence: YVVGRKNCAILIENDQSISRNHAVLTANFSVTNLSQTDEIPVLTLKDNSKYGTSVNEEKM | ||||||
Region | 326-345 | Disordered | ||||
Sequence: RGHPSTGLKTTTPGPSLSQG | ||||||
Compositional bias | 330-344 | Polar residues | ||||
Sequence: STGLKTTTPGPSLSQ | ||||||
Compositional bias | 426-460 | Polar residues | ||||
Sequence: IPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQ | ||||||
Region | 426-479 | Disordered | ||||
Sequence: IPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQPSTKKRERDEENQEMSSCK | ||||||
Compositional bias | 461-477 | Basic and acidic residues | ||||
Sequence: PSTKKRERDEENQEMSS | ||||||
Compositional bias | 505-538 | Polar residues | ||||
Sequence: EQHLSQNEPVDTNSDDNLFTDTDLKSSVKNSASK | ||||||
Region | 505-552 | Disordered | ||||
Sequence: EQHLSQNEPVDTNSDDNLFTDTDLKSSVKNSASKSHASEKLRSNKKRE |
Sequence similarities
Belongs to the Nibrin family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length754
- Mass (Da)85,038
- Last updated2011-02-08 v1
- ChecksumBEE9B10A13EF1EEE
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A7N9CS86 | A0A7N9CS86_MACFA | NBN | 776 | ||
A0A2K5USC9 | A0A2K5USC9_MACFA | NBN | 739 | ||
A0A7N9CV02 | A0A7N9CV02_MACFA | NBN | 382 | ||
A0A7N9I9I9 | A0A7N9I9I9_MACFA | NBN | 705 |
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 330-344 | Polar residues | ||||
Sequence: STGLKTTTPGPSLSQ | ||||||
Compositional bias | 426-460 | Polar residues | ||||
Sequence: IPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQ | ||||||
Compositional bias | 461-477 | Basic and acidic residues | ||||
Sequence: PSTKKRERDEENQEMSS | ||||||
Compositional bias | 505-538 | Polar residues | ||||
Sequence: EQHLSQNEPVDTNSDDNLFTDTDLKSSVKNSASK | ||||||
Non-terminal residue | 754 | |||||
Sequence: R |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HM486838 EMBL· GenBank· DDBJ | ADQ01174.1 EMBL· GenBank· DDBJ | mRNA |