E5DCW3 · E5DCW3_ACROI

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

134650100150200250300
TypeIDPosition(s)Description
Binding site50Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site64Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site149Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site163Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site168a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processrespiratory electron transport chain

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Passeriformes > Sylvioidea > Sylviidae > Acrocephalinae > Acrocephalus

Accessions

  • Primary accession
    E5DCW3

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-37Helical
Transmembrane49-70Helical
Transmembrane82-100Helical
Transmembrane107-125Helical
Transmembrane145-167Helical
Transmembrane196-217Helical
Transmembrane255-274Helical
Transmembrane286-307Helical
Transmembrane313-339Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-176Cytochrome b/b6 N-terminal region profile
Domain177-346Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    346
  • Mass (Da)
    38,421
  • Last updated
    2011-02-08 v1
  • Checksum
    AD70403359A93543
GSLLGVCLVTQIVTGLLLAMHYTADTSLAFASVAHVCRDVQFGWLIRNLHANGASFFFICIYFHIGRGFYYGSYLNKETWNIGVVLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGLTLVHLTLLHETGSNNPLGIPSDCDKIPFHPYYSVKDILGFAFMFILLASLALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLMPLLHTSKLRSMTFRPLSQILFWALVANLLVLTWVGSQPVEHPFIIIGQLASLSYFTIILVLFPLASIFENKLLKL

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue346

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GU247952
EMBL· GenBank· DDBJ
ACZ69556.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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