E5AD87 · SHO1_LEPMJ

Function

function

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    High osmolarity signaling protein SHO1
  • Alternative names
    • Osmosensor SHO1

Gene names

    • Name
      SHO1
    • ORF names
      Lema_P012260

Organism names

Accessions

  • Primary accession
    E5AD87

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-37Cytoplasmic
Transmembrane38-58Helical
Topological domain59-67Extracellular
Transmembrane68-88Helical
Topological domain89-96Cytoplasmic
Transmembrane97-117Helical
Topological domain118-119Extracellular
Transmembrane120-140Helical
Topological domain141-336Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004103801-336High osmolarity signaling protein SHO1

Interaction

Subunit

Forms homooligomers.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region186-210Disordered
Compositional bias194-210Polar residues
Region226-273Disordered
Compositional bias242-272Polar residues
Domain277-336SH3

Sequence similarities

Belongs to the SHO1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    36,094
  • Last updated
    2011-02-08 v1
  • Checksum
    DC83633087B07C38
MPVYGSVSSPSLRKMENGYGHGQRASLSFGRIIGDPFALATISIGVLAWIIAFVSSIISAIHGGFPNFAWWTLVFMFFCIAGVTVTVASDAERTYHVAIVGFLAAGLVFTTSSVNSLVYSPIAPFEAAAAGYILLSMIAVRDCISSSLSQPATNAPRPQIVWIFYYGSQPQASHRAFVDSYALHKEHPGSRSSRPISHGYTNRPETQVASQAPQMYTSAQLNGFETSSPVSGYPGGPAGANGRNSSVPQFGGMPNNGIPNAATPTQDEAHQQEASIEYPYRAKAIYSYEANPDDANEISFQKHDVLEVSDVSGRWWQAKKPNGETGIAPSNYLILL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias194-210Polar residues
Compositional bias242-272Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FP929139
EMBL· GenBank· DDBJ
CBY02439.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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