E5AD87 · SHO1_LEPMJ
- ProteinHigh osmolarity signaling protein SHO1
- GeneSHO1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids336 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameHigh osmolarity signaling protein SHO1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Pleosporineae > Leptosphaeriaceae > Plenodomus > Plenodomus lingam/Leptosphaeria maculans species complex
Accessions
- Primary accessionE5AD87
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-37 | Cytoplasmic | ||||
Sequence: MPVYGSVSSPSLRKMENGYGHGQRASLSFGRIIGDPF | ||||||
Transmembrane | 38-58 | Helical | ||||
Sequence: ALATISIGVLAWIIAFVSSII | ||||||
Topological domain | 59-67 | Extracellular | ||||
Sequence: SAIHGGFPN | ||||||
Transmembrane | 68-88 | Helical | ||||
Sequence: FAWWTLVFMFFCIAGVTVTVA | ||||||
Topological domain | 89-96 | Cytoplasmic | ||||
Sequence: SDAERTYH | ||||||
Transmembrane | 97-117 | Helical | ||||
Sequence: VAIVGFLAAGLVFTTSSVNSL | ||||||
Topological domain | 118-119 | Extracellular | ||||
Sequence: VY | ||||||
Transmembrane | 120-140 | Helical | ||||
Sequence: SPIAPFEAAAAGYILLSMIAV | ||||||
Topological domain | 141-336 | Cytoplasmic | ||||
Sequence: RDCISSSLSQPATNAPRPQIVWIFYYGSQPQASHRAFVDSYALHKEHPGSRSSRPISHGYTNRPETQVASQAPQMYTSAQLNGFETSSPVSGYPGGPAGANGRNSSVPQFGGMPNNGIPNAATPTQDEAHQQEASIEYPYRAKAIYSYEANPDDANEISFQKHDVLEVSDVSGRWWQAKKPNGETGIAPSNYLILL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000410380 | 1-336 | High osmolarity signaling protein SHO1 | |||
Sequence: MPVYGSVSSPSLRKMENGYGHGQRASLSFGRIIGDPFALATISIGVLAWIIAFVSSIISAIHGGFPNFAWWTLVFMFFCIAGVTVTVASDAERTYHVAIVGFLAAGLVFTTSSVNSLVYSPIAPFEAAAAGYILLSMIAVRDCISSSLSQPATNAPRPQIVWIFYYGSQPQASHRAFVDSYALHKEHPGSRSSRPISHGYTNRPETQVASQAPQMYTSAQLNGFETSSPVSGYPGGPAGANGRNSSVPQFGGMPNNGIPNAATPTQDEAHQQEASIEYPYRAKAIYSYEANPDDANEISFQKHDVLEVSDVSGRWWQAKKPNGETGIAPSNYLILL |
Interaction
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 186-210 | Disordered | ||||
Sequence: EHPGSRSSRPISHGYTNRPETQVAS | ||||||
Compositional bias | 194-210 | Polar residues | ||||
Sequence: RPISHGYTNRPETQVAS | ||||||
Region | 226-273 | Disordered | ||||
Sequence: TSSPVSGYPGGPAGANGRNSSVPQFGGMPNNGIPNAATPTQDEAHQQE | ||||||
Compositional bias | 242-272 | Polar residues | ||||
Sequence: GRNSSVPQFGGMPNNGIPNAATPTQDEAHQQ | ||||||
Domain | 277-336 | SH3 | ||||
Sequence: EYPYRAKAIYSYEANPDDANEISFQKHDVLEVSDVSGRWWQAKKPNGETGIAPSNYLILL |
Sequence similarities
Belongs to the SHO1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length336
- Mass (Da)36,094
- Last updated2011-02-08 v1
- ChecksumDC83633087B07C38
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 194-210 | Polar residues | ||||
Sequence: RPISHGYTNRPETQVAS | ||||||
Compositional bias | 242-272 | Polar residues | ||||
Sequence: GRNSSVPQFGGMPNNGIPNAATPTQDEAHQQ |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FP929139 EMBL· GenBank· DDBJ | CBY02439.1 EMBL· GenBank· DDBJ | Genomic DNA |