E4ZUB5 · LCPS_LEPMJ

Function

function

Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).

Catalytic activity

Pathway

Carotenoid biosynthesis; beta-carotene biosynthesis.
Carotenoid biosynthesis; phytoene biosynthesis; all-trans-phytoene from geranylgeranyl diphosphate: step 1/1.

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function15-cis-phytoene synthase activity
Molecular Functionfarnesyl-diphosphate farnesyltransferase activity
Molecular Functionfarnesyltranstransferase activity
Molecular Functiongeranylgeranyl-diphosphate geranylgeranyltransferase activity
Molecular Functionintramolecular lyase activity
Molecular Functionlycopene beta cyclase activity
Biological Processcarotenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional lycopene cyclase/phytoene synthase

Including 2 domains:

  • Recommended name
    Lycopene beta-cyclase
  • EC number
  • Alternative names
    • Lycopene cyclase
  • Recommended name
    Phytoene synthase
  • EC number

Gene names

    • ORF names
      Lema_P114090.1

Organism names

Accessions

  • Primary accession
    E4ZUB5

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane3-23Helical
Transmembrane35-55Helical
Transmembrane65-85Helical
Transmembrane120-140Helical
Transmembrane152-172Helical
Transmembrane173-193Helical
Transmembrane221-241Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004092371-581Bifunctional lycopene cyclase/phytoene synthase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-243Lycopene beta-cyclase
Region250-581Phytoene synthase

Sequence similarities

In the N-terminal section; belongs to the lycopene beta-cyclase family.
In the C-terminal section; belongs to the phytoene/squalene synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    581
  • Mass (Da)
    65,807
  • Last updated
    2011-02-08 v1
  • Checksum
    AE5B91B31A0FBDD1
MGFDYALVHLKYTIPPAVLLTLLYRPLLTKIDVYKVAFLVTIAVVATIPWDSYLIRNRIWSYPDHVIIGPTLFDIPLEEVFFFVVQTYNTSLLYLVLSKPTFQPVYLCTERDELHGSWRLKRLIGQAILLGAIAWGWFCVRERGLGTYTGLILIWAGPFLLLLWSLAYQFIIGLPFTNTLLPIVLPTLYLWIVDTLALRRGTWVISPGTKFGVHLWDGLEIEEALFFLLTNVLIVFGQLAFDNALAVLYAFPHLFPDPSLLPSPATLIRSLLTSCAQYDEARLTGFREAVSRLKRKSRSFYLASSTFQGPLRMDLLLLYSFCRVADDLVDNAATTEEARQWIAKLHKFLDNVYRKDVVCSSVTDQVRKEFPLDTHSALLQLPCCKLSAEPLRDLLRGFEMDLEFNSTSPIQSTEDLVLYSERVAGTVAQMCIQLIFHLYPSSLTAEKRHKVVAAGNSMGVALQYVNIARDIGVDAKIGRVYLPTDWLSEVGLNCDTVLKDPKDPRIEALRGRLLDDAFSFYEEAKLAIAQLPIEAQGPIRVAVESYMEIGRTLKQDGFIVKAGRATVPKWRRVLVAWRTLN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FP929126
EMBL· GenBank· DDBJ
CBX94994.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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