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E4V3P6 · E4V3P6_ARTGP

Function

Catalytic activity

Pathway

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
Molecular FunctionN6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
Biological Process'de novo' AMP biosynthetic process
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenylosuccinate lyase
  • EC number
  • Short names
    ASL
  • Alternative names
    • Adenylosuccinase

Gene names

    • ORF names
      MGYG_07627

Organism names

Accessions

  • Primary accession
    E4V3P6

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Subunit

Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain372-456Adenylosuccinate lyase C-terminal

Sequence similarities

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    53,880
  • Last updated
    2011-02-08 v1
  • MD5 Checksum
    A6803F73E347AF421CAB53F575CC3C4D
MSANDQYQTPLASRYASNEMKTIFSARERASTWRKLWLWLAEAEKELGIKQISDEAIEAIKANVTVSDEAFKVAAVEERRRRHDVMAHVYALEKDAPAAAGVIHLGATSCYDNADLIFIRDALDLILPKLAKVIHNLAQFSLKYKDLPALGFTHYQAAQAITLGRRGAQWLQDLVMDLEDIEYVRAGLKFRGAQGTTGTQASFMEIFQNDASKIDKLNEILCKKAGFSSCYDISTQTYTRKVDLRIANALAALGATAVRIATDLRHLAHDKVMEEPFEKDQIGSSAMAYKRNPNAGIESAALAGKLSNVSANFSETFSGQWLERTLDDSAIRRIDIPEMFLMADAILISLDNITNGLVVYPAIVNSQLREELPFMATENIIMKLCSHGVSRQEAHEEIRVLSHQAAHVVKMEGGKNDLIERIKKTEFFKPVWDEIDGLLDTKLFIGRSPEIVERYAGVGGPVEKKLEQYKEYIMSTATAELSV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS989828
EMBL· GenBank· DDBJ
EFR04620.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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