E4MQ50 · E4MQ50_CAPOC

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    ppa
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site498Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      ppa
    • Synonyms
      hppA
    • ORF names
      HMPREF1977_0510

Organism names

  • Taxonomic identifier
  • Strain
    • F0287
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Capnocytophaga

Accessions

  • Primary accession
    E4MQ50

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical
Transmembrane58-77Helical
Transmembrane83-106Helical
Transmembrane127-155Helical
Transmembrane245-263Helical
Transmembrane284-306Helical
Transmembrane326-344Helical
Transmembrane365-383Helical
Transmembrane424-447Helical
Transmembrane504-523Helical
Transmembrane535-555Helical
Transmembrane603-620Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain802-919OmpA-like

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    919
  • Mass (Da)
    96,489
  • Last updated
    2011-02-08 v1
  • Checksum
    4DA06EB86B5D78C1
MEKMMLYLPLALAIFGLIFMITKALWVNKQTTGNDRMQSISKSIKEGAMAFLNAEYRILALFVIIASIALFIVSRMVETSHWLIVVAFVCGAFFSALAGNIGMRIATNANVRTTEAARTSLPKALKVSFGGGTVMGLGVAGLAVLGLSLFFILFVNTFVVGGKSFYDEMTLVLEALAGFSLGAESIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGMGADLFGSYVATVLASMVLGNYVIKDMAIANGGTFTDAFGGLGPILLPLVIAGVGIIASIIGTFCIGIKNNDAKEKQVQSSLNTGNYVALGLTLVACFFLIKYMLPETIQMSFFGEGMKEIASINVFYATIVGLAVGLLISAITEHFTALGKKPVLNIVRNSSTGAATNIIAGLATGMKSTFGSVLLFAVAIWGSYSLAGFYGVAIAASAMMATTAMQLAIDAFGPIADNAGGVAEMSELPKEVRQRTDILDSVGNTTAAVGKGFAIASAALTALALFAAYVTFTGISGINIFKANVLAALFIGGMIPVIFSALAMQSVGKAAMDMVNEVRRQFREIPGIMEGKGTPEYGRCVDISTKAALREMMLPGAITIITPIIIGFVMGAEALGAYMAGVAVSGVVWAIFQNNAGGAWDNAKKSFEAGVEINGQMTYKGSDAHKAAVTGDTVGDPFKDTSGPSMNILIKLTCLVGLVIAPILGGHTADATGTPVEAQIRQGEGEGVMPVEEVVVIEEGKLNADGDFEYNVGDLFQLSLFDNTMLEVGKNSSEAHLVKLIEDKNLTTPEQFKDNWITLDRTYFKTGSDELTEGSEQQLKNIVAILKAYPKAAIRLGGYTDNTGSVEGNKKLSERRANSVLNKLVALGANKAQLSAQGYGAEHPLCPANDTPECKAKNRRIDIRLTAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AEOH01000012
EMBL· GenBank· DDBJ
EFS98179.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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