E3QRY8 · GFA_COLGM
- ProteinPutative glutathione-dependent formaldehyde-activating enzyme
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids191 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
Catalytic activity
- S-(hydroxymethyl)glutathione = glutathione + formaldehyde
Cofactor
Note: Binds 2 Zn2+ ions per subunit.
Pathway
One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 27 | Zn2+ 1 (UniProtKB | ChEBI); structural | |||
Binding site | 29 | Zn2+ 1 (UniProtKB | ChEBI); structural | |||
Binding site | 48 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | |||
Binding site | 50 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | |||
Binding site | 53 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | |||
Binding site | 95 | Zn2+ 1 (UniProtKB | ChEBI); structural | |||
Binding site | 98 | Zn2+ 1 (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | S-(hydroxymethyl)glutathione synthase activity | |
Molecular Function | zinc ion binding | |
Biological Process | formaldehyde catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative glutathione-dependent formaldehyde-activating enzyme
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Glomerellales > Glomerellaceae > Colletotrichum > Colletotrichum graminicola species complex
Accessions
- Primary accessionE3QRY8
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000406158 | 1-191 | Putative glutathione-dependent formaldehyde-activating enzyme | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length191
- Mass (Da)20,901
- Last updated2011-01-11 v1
- ChecksumF0BC9194866BA9B4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG697372 EMBL· GenBank· DDBJ | EFQ33626.1 EMBL· GenBank· DDBJ | Genomic DNA |