E3GCF1 · GPDQ_ENTLS
- ProteinGlycerophosphodiester phosphodiesterase GpdQ
- GenegpdQ
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids278 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydrolysis of the 3'-5' phosphodiester bond of glycerophosphodiesters such as glycerophosphorylethanolamine (GPE), a typical phospholipid metabolite.
Catalytic activity
- a sn-glycero-3-phosphodiester + H2O = an alcohol + H+ + sn-glycerol 3-phosphate
- H2O + sn-glycero-3-phosphoethanolamine = ethanolamine + H+ + sn-glycerol 3-phosphate
Cofactor
Note: Binds 2 Fe2+ ions per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 8 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 10 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 50 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 50 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 80 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 156 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 195 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 197 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3',5'-cyclic-AMP phosphodiesterase activity | |
Molecular Function | glycerophosphodiester phosphodiesterase activity | |
Molecular Function | metal ion binding | |
Biological Process | glycerol metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycerophosphodiester phosphodiesterase GpdQ
- EC number
- Short namesGDPD ; Glycerophosphoryl diester phosphodiesterase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Pluralibacter
Accessions
- Primary accessionE3GCF1
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000413367 | 1-278 | Glycerophosphodiester phosphodiesterase GpdQ | |||
Sequence: MLLAHISDTHFRSQNHKLYGFIDVNAGNADVVSQLNGLRERPDAVVVSGDIVNCGRPEEYQVARQVLGALRYPLLLIPGNHDDKACFLEYLRPLCPQLGSDPQNMRYAIDDFATRLLFIDSSLAGHAKGWLTDNTVAWLEAQLSDAGDKPTAVFMHHPPLPLGNAQMDPIACENGHRLLALVERFPSLVRIFCGHNHNLTMTQYRQATIATLPATVHQVPYCHEDTRPYYDMSPPSCLMHRQVGEQWVSYQHSLAHYAGPWLYDEHISCPTDERRSPC |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length278
- Mass (Da)31,308
- Last updated2011-01-11 v1
- ChecksumCFF0D7D4DDB3AF10
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002272 EMBL· GenBank· DDBJ | ADO50122.1 EMBL· GenBank· DDBJ | Genomic DNA |