E2QUD0 · GATA_CANLF

Function

function

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

Features

Showing features for active site.

152650100150200250300350400450500
TypeIDPosition(s)Description
Active site76Charge relay system
Active site171Charge relay system
Active site195Acyl-ester intermediate

GO annotations

AspectTerm
Cellular Componentglutamyl-tRNA(Gln) amidotransferase complex
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular Functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Biological Processglutaminyl-tRNAGln biosynthesis via transamidation
Biological Processmitochondrial translation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
  • EC number
  • Short names
    Glu-AdT subunit A
  • Alternative names
    • Glutaminyl-tRNA synthase-like protein 1

Gene names

    • Name
      QRSL1

Organism names

Accessions

  • Primary accession
    E2QUD0

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004133311-526Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

Proteomic databases

Interaction

Subunit

Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the amidase family. GatA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    526
  • Mass (Da)
    57,329
  • Last updated
    2010-11-30 v1
  • Checksum
    4ECFD1177490564B
MLGRTLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKKGHSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYVPPYNATVVQKLLDQGAVLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYKEKTKHKAHGENEDSNWLITGGSSGGSAAAVATFTCFAALGSDTGGSTRNPAAHCGVVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGMLAGHDPKDSTTVQDPVKPFTLPSLTDVSKLCIGIPKEYLTPELSSEVQSLWSKAANLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLEYGHRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFIKAQKVRRLIANDFVNVFNSGVDVLLTPTTLREAVPYQEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSPVALSNQGLPVGLQFIGRAFHDQQLLTVAKWFEKQVQFPVTQLQELMDDCSSVFEIEKLASVSLKQ

Keywords

Similar Proteins

Disclaimer

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