E2Q767 · E2Q767_STRCL

  • Protein
    Glucosamine-6-phosphate deaminase
  • Gene
    nagB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).

Pathway

Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.

Features

Showing features for active site, site.

Type
IDPosition(s)Description
Active site101Proton acceptor; for enolization step
Active site170For ring-opening step
Active site172Proton acceptor; for ring-opening step
Active site177For ring-opening step
Site180Part of the allosteric site
Site187Part of the allosteric site
Site189Part of the allosteric site
Site190Part of the allosteric site

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglucosamine-6-phosphate deaminase activity
Molecular Functionidentical protein binding
Biological Processcarbohydrate metabolic process
Biological Processglucosamine catabolic process
Biological ProcessN-acetylglucosamine catabolic process
Biological ProcessN-acetylneuraminate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucosamine-6-phosphate deaminase
  • EC number
  • Alternative names
    • GlcN6P deaminase
      (GNPDA
      )
    • Glucosamine-6-phosphate isomerase

Gene names

    • Name
      nagB
    • ORF names
      SCLAV_0238

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    E2Q767

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain44-263Glucosamine/galactosamine-6-phosphate isomerase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    294
  • Mass (Da)
    30,737
  • Last updated
    2010-11-30 v1
  • Checksum
    EEB7E33200734444
MSLHGAGTRQIACSPGRLVYTIALPETHPETGIFVEVVIVPDAAAGGELIAEAMADLLRRKPDALLGVATGSTPLPIYEALAAKVRAAEVDASRARICQLDEYVGLPFGHPESYRSVVLREVVEPLGLPESSFLGPDGTTDDVAAACAAYDSALAGAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRQDNARFFDSPDEVPHHVITQGIGTILEARHLVLLATGAAKAEAVALAVEGPLSALVPASALQLHAHATVVVDEAAASRLKLADYFRATWAAKPDWQGI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM000913
EMBL· GenBank· DDBJ
EFG05314.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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