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E2F6L1 · E2F6L1_PANTR

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      ND5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • CP466
    • Makata
    • Vaillant
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan

Accessions

  • Primary accession
    E2F6L1

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane84-105Helical
Transmembrane117-134Helical
Transmembrane140-160Helical
Transmembrane172-191Helical
Transmembrane211-233Helical
Transmembrane245-266Helical
Transmembrane272-294Helical
Transmembrane301-319Helical
Transmembrane325-347Helical
Transmembrane368-386Helical
Transmembrane406-428Helical
Transmembrane584-602Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_500841358422-603NADH-ubiquinone oxidoreductase chain 5

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain68-118NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain134-419NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain422-602NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    603
  • Mass (Da)
    67,256
  • Last updated
    2010-11-30 v1
  • MD5 Checksum
    2A79D6F211BD4A063CF2B9A6997BC86A
MTMYATMTTLTLTSLIPPILATLINPNKKNSYPHYVKSIIASTFIISLFPTTMFMCLDQEAIISNWHWATTQTTQLSLSFKLDYFSMTFIPVALFVTWSIMEFSLWYMDSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYARTDANTAAIQAILYNRIGDIGFVLALAWFLLHSNSWDPQQMILLNTNTDLTPLLGFLLAAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRFYPLAENNPLIQTLTLCLGAITTLFAAVCALTQNDIKKIVAFSTSSQLGLMMVTIGINQPYLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTIGNLALAGMPFLTGFYSKDLIIETANMSYTNAWALSITLIATSLTSAYSTRMILLTLTGQPRFPTLTNINENNPTLLNPIKRLTVGSLFAGFLITNNILPMSTSQVTIPLYLKLTALGVTSLGLLTALDLNYLTNKLKMKSPLYTFYFSNMLGFYPDIMHRSIPYLGLLTSQNLPLLLLDLTWLEKLLPKTISQYQISASITTSTQKGMIKLYFLSFFFPLILTLLLIA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM068573
EMBL· GenBank· DDBJ
ADF87997.1
EMBL· GenBank· DDBJ
Genomic DNA
JN191216
EMBL· GenBank· DDBJ
AEO20794.1
EMBL· GenBank· DDBJ
Genomic DNA
JN191224
EMBL· GenBank· DDBJ
AEO20898.1
EMBL· GenBank· DDBJ
Genomic DNA
KX211959
EMBL· GenBank· DDBJ
ANP95882.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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