E2BK77 · E2BK77_HARSA
- Protein[heparan sulfate]-glucosamine N-sulfotransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids731 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Pathway
Glycan metabolism; heparan sulfate biosynthesis.
Glycan metabolism; heparin biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 460 | For sulfotransferase activity | |||
Binding site | 558 | 3'-phosphoadenylyl sulfate (UniProtKB | ChEBI) | |||
Binding site | 679-683 | 3'-phosphoadenylyl sulfate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Golgi apparatus | |
Cellular Component | membrane | |
Molecular Function | [heparan sulfate]-glucosamine N-sulfotransferase activity | |
Molecular Function | deacetylase activity | |
Biological Process | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | |
Biological Process | heparin biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name[heparan sulfate]-glucosamine N-sulfotransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Formicoidea > Formicidae > Ponerinae > Ponerini > Harpegnathos
Accessions
- Primary accessionE2BK77
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Single-pass type II membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 664↔674 | ||||
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-361 | Heparan sulphate-N-deacetylase | |||
Domain | 451-692 | Sulfotransferase | |||
Sequence similarities
Belongs to the sulfotransferase 1 family. NDST subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length731
- Mass (Da)84,604
- Last updated2010-11-30 v1
- Checksum8446619AAA30EE3B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GL448770 EMBL· GenBank· DDBJ | EFN83874.1 EMBL· GenBank· DDBJ | Genomic DNA |