E2BK77 · E2BK77_HARSA

Function

Pathway

Glycan metabolism; heparan sulfate biosynthesis.
Glycan metabolism; heparin biosynthesis.

Features

Showing features for active site, binding site.

1731100200300400500600700
Type
IDPosition(s)Description
Active site460For sulfotransferase activity
Binding site5583'-phosphoadenylyl sulfate (UniProtKB | ChEBI)
Binding site679-6833'-phosphoadenylyl sulfate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentGolgi apparatus
Cellular Componentmembrane
Molecular Function[heparan sulfate]-glucosamine N-sulfotransferase activity
Molecular Functiondeacetylase activity
Biological Processheparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
Biological Processheparin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    [heparan sulfate]-glucosamine N-sulfotransferase
  • EC number

Gene names

    • ORF names
      EAI_00427

Organism names

  • Taxonomic identifier
  • Strain
    • R22 G/1
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Formicoidea > Formicidae > Ponerinae > Ponerini > Harpegnathos

Accessions

  • Primary accession
    E2BK77

Proteomes

Subcellular Location

Golgi apparatus membrane
; Single-pass type II membrane protein

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond664↔674

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-361Heparan sulphate-N-deacetylase
Domain451-692Sulfotransferase

Sequence similarities

Belongs to the sulfotransferase 1 family. NDST subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    731
  • Mass (Da)
    84,604
  • Last updated
    2010-11-30 v1
  • Checksum
    8446619AAA30EE3B
MDKWNRELLDKYCREYSVGIVGFAPPGEESLVGAQLKGFPLFIHTNLRLKDAQLNAASPILRLTRSGETAWGPLPGGDWTIFQANHSTYEPLAWAHRDSLDYPANKSPLATVIQDHGRYDGIQRVLFGSGLRFWLHKLLLLDSLSYLSHGQLSLSLNRMILVDVDDIFVGEKSTRLRKDDVMALLATQQRIQALVPGFKFNLGFSGKYFHHGTAEENLGDDMLLENVDRFTWFSHMWNHQQPHLYENVTHLQLDMALNKQFAKDHGIPTGSGYSVSPHHSGVYPVHEGLYEAWKRVWNIKVTSTEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTIFIERYPGGREKLDESIQGGELFQTIVYNPINIFMTHMSNYGNDRLALYTFESVIKFIQCWTNLRLSSAPPLQLGERYFQLYPEEADPVWGNPCDDQRHQKIWSRNKTCDQLPRFLVIGPQKTGTTALYTFLSIHPAISSNLPSPDTFEEIQFFNGKNYYKGLDWYMSFFPTAKNESSRYLFEKSATYFDGELVPRRAHALLPRAKLITILLSPARRAYSWYQHTRVHGDPVANNYSFHSVITASDSAPKPLRDLRNRCLNPGKYAQHLERWLSFYVPQQLHIIDGEQLRQNPVETLHELQRFLKITPAFNYSSHLRYDPKKGFFCQVTNEDRTKCLGKSKGRQYPPMEDRSYKLLQRYYLSHNTALVKLLKRLGSRTIPQWLKEDLTDTVMT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL448770
EMBL· GenBank· DDBJ
EFN83874.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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