E1ZY18 · E1ZY18_CAMFO

Function

function

Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmembrane
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number

Gene names

    • ORF names
      EAG_09970

Organism names

  • Taxonomic identifier
  • Strain
    • C129
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Formicoidea > Formicidae > Formicinae > Camponotus

Accessions

  • Primary accession
    E1ZY18

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane149-169Helical
Transmembrane189-209Helical

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain280-455Glucose-6-phosphate dehydrogenase NAD-binding
Domain457-749Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    758
  • Mass (Da)
    88,451
  • Last updated
    2010-11-30 v1
  • Checksum
    26AB9AF1435BF281
MIWLLFLFIHEILSNNGNTILKNLGEKEYSLIKAKSSLPQHGKCWHMALQTLQDSCDKLNDYEHSLLALRLANCFLEDSGHITYDCHLNQLEDERRKCINEMGDRAFSVYNEFYIHATHICFFLNHEAWQSEIDNTINFSSKRTVDARVTLFSILSLNIVIERILVQYYNRTVPQSPDNKAQLLSTTWLYRNIALILCAITLICTYYYYKDKHLENCKTLQRIEQQLNVIQKTVAVSNNIEPIQTSTEESLQYIRQSLTSEEMDHLEGTHFDRLIPHLFVTLGASGDLAKKKIYPTLWWLFRDNLLPKPTTFIGYARSKLTVQQLREKCHPYMKVKSSEEEKYEEFWKLNHYVAGVYDKRDDFERLDRELQKYEQGQVAHRLFYLALPPSVFESVTLRLRLTCMGNKGWTRIIIEKPFGHDAISSQKLSENLASLFSEEQIYRIDHYLGKEMVQNLMTLRFGNRVFNPSWNRDNIASVQITFKEPFGTQGRGGYFDEFGIIRDVMQNHLLQILSLVAMEKPASCHPDDIRNEKVKVLRCIKELQLENVILGQYVGDPDAEDPEAHLGYLDDPTVPTSSNTPTFALAVLKINNERWDGVPFILRCGKALNERKAEVRIQYHDVPGDIFDGKPKRNEMVIRVQPGEALYIKMMTKSPGITFDMEETELDLTYGNRYKDLKLPDAYERLILDVFCGSQMHFVRNDELQEAWRIFTPLLHRIEKEKIQPVPYKYGSRGPKEADDMAKRNNFAYYGSYKWVKP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GL435171
EMBL· GenBank· DDBJ
EFN73867.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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