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E1JID8 · E1JID8_DROME

Function

Pathway

Glycan metabolism; heparan sulfate biosynthesis.
Glycan metabolism; heparin biosynthesis.

Features

Showing features for active site, binding site.

110481002003004005006007008009001,000
Type
IDPosition(s)Description
Active site768For sulfotransferase activity
Binding site8773'-phosphoadenylyl sulfate (UniProtKB | ChEBI)
Binding site9823'-phosphoadenylyl sulfate (UniProtKB | ChEBI)
Binding site998-10023'-phosphoadenylyl sulfate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function[heparan sulfate]-glucosamine N-sulfotransferase activity
Molecular Functionhydrolase activity
Biological Processheparan sulfate proteoglycan biosynthetic process
Biological Processheparin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    [heparan sulfate]-glucosamine N-sulfotransferase
  • EC number

Gene names

    • Name
      sfl
    • Synonyms
      CT24567
      , Dmel\CG8339
      , dw
      , l(3)03844
      , lincRNA.S4253
      , NDST
      , Sfl
      , sfl-RA
    • ORF names
      CG8339
      , Dmel_CG8339

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    E1JID8

Proteomes

Organism-specific databases

Subcellular Location

Golgi apparatus membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane173-191Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond983↔993

Keywords

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain240-669Heparan sulphate-N-deacetylase
Domain759-1018Sulfotransferase

Sequence similarities

Belongs to the sulfotransferase 1 family. NDST subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,048
  • Mass (Da)
    118,590
  • Last updated
    2010-11-30 v1
  • MD5 Checksum
    5EB87152CBDE63488D18817A9B8B1D5F
MTISGGNQHNNNANRKYEKLIKQPQMQFGSSVTGTQTDVDSCRDADADANAVRQDFSNFNKHFGNGHAITDRTMLLRLEDDVTTAAGIVTYKGKSNGNGNGNGNGSIGSISLDFNGSPTSSTSIGIASGSSSNTHLASGGGVGGIGGSEPAGWMCHCCNLIARRCFGINVRRCVLALLAITMVSIFYYTHYVDTGVFNGLIQRDTHPAPIINCRMINSGGKHIRNASPAPDHRSEARLRIDPKVLVFVETTYSGLGRDIAELLVYNRIKYKIEVAGKSLPVLTNLDKGRYGVIVFENLDKYLNMDKWNRELLDKYCREYSVGIVGFVSPSEETLVGAQLRDFPLFVNTNLRLRDASLNPLSSVLRLTRAGETAWGALPGDDWAVFQHNHSTYEPVEWAQRNTQEYPADSVGQVQLPLTTVLQDRGQLDGIQRVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRLRPDDVRALIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQPHLYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTSTEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQTIVYNPINIFMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVRHKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHNTALVKLLKKLGSRPIPQWLKDDLSTGT

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9V3L1NDST_DROMEsfl1048
A0A9F2H0Y2A0A9F2H0Y2_DROMEsfl1129
Q4V3Y9Q4V3Y9_DROMEsfl199

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014296
EMBL· GenBank· DDBJ
ACZ94625.1
EMBL· GenBank· DDBJ
Genomic DNA
BT132640
EMBL· GenBank· DDBJ
AEQ05538.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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