E1JID8 · E1JID8_DROME
- Protein[heparan sulfate]-glucosamine N-sulfotransferase
- Genesfl
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1048 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Pathway
Glycan metabolism; heparan sulfate biosynthesis.
Glycan metabolism; heparin biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 768 | For sulfotransferase activity | |||
Binding site | 877 | 3'-phosphoadenylyl sulfate (UniProtKB | ChEBI) | |||
Binding site | 982 | 3'-phosphoadenylyl sulfate (UniProtKB | ChEBI) | |||
Binding site | 998-1002 | 3'-phosphoadenylyl sulfate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | [heparan sulfate]-glucosamine N-sulfotransferase activity | |
Molecular Function | hydrolase activity | |
Biological Process | heparan sulfate proteoglycan biosynthetic process | |
Biological Process | heparin biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name[heparan sulfate]-glucosamine N-sulfotransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionE1JID8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Single-pass type II membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 173-191 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 983↔993 | ||||
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 240-669 | Heparan sulphate-N-deacetylase | |||
Domain | 759-1018 | Sulfotransferase | |||
Sequence similarities
Belongs to the sulfotransferase 1 family. NDST subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,048
- Mass (Da)118,590
- Last updated2010-11-30 v1
- MD5 Checksum5EB87152CBDE63488D18817A9B8B1D5F
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9V3L1 | NDST_DROME | sfl | 1048 | ||
A0A9F2H0Y2 | A0A9F2H0Y2_DROME | sfl | 1129 | ||
Q4V3Y9 | Q4V3Y9_DROME | sfl | 199 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | ACZ94625.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT132640 EMBL· GenBank· DDBJ | AEQ05538.1 EMBL· GenBank· DDBJ | mRNA |