Infection and chronic disease activate a systemic brain-muscle signaling axis.Yang S., Tian M., Dai Y., Wang R., Yamada S., Feng S., Wang Y., Chhangani D., Ou T.[...], Johnson A.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCSci Immunol 9:eadm7908-eadm7908 (2024)Mapped to28
An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context.Suarez-Grimalt R., Grunwald Kadow I.C., Scheunemann L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCLearn Mem 31:a053918-a053918 (2024)Mapped to10
IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.Prakash A., Fenner F., Shit B., Salminen T.S., Monteith K.M., Khan I., Vale P.F.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCPLoS Pathog 20:e1012308-e1012308 (2024)Mapped to32
High-fat diets induce inflammatory IMD/NFkappaB signaling via gut microbiota remodeling in pii>Drosophilapi/i>.Wang J., Gu J., Yi J., Li J., Li W., Zhai Z.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCFront Cell Infect Microbiol 14:1347716-1347716 (2024)Mapped to41
Bacterial peptidoglycan serves as a critical modulator of the gut-immune- brain axis in Drosophila.Fioriti F., Rifflet A., Gomperts Boneca I., Zugasti O., Royet J.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCBrain Behav Immun 119:878-897 (2024)Mapped to99+
When the microbiome shapes the host: immune evolution implications for infectious disease.Hanson M.A.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCPhilos Trans R Soc Lond B Biol Sci 379:20230061-20230061 (2024)Mapped to29
A humoral stress response protects Drosophila tissues from antimicrobial peptides.Rommelaere S., Carboni A., Bada Juarez J.F., Boquete J.P., Abriata L.A., Teixeira Pinto Meireles F., Rukes V., Vincent C., Kondo S.[...], Lemaitre B.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCCurr Biol 34:1426-1437.e6 (2024)Mapped to281
Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system.Zhang P., Catterson J.H., Gronke S., Partridge L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCNat Aging 4:491-509 (2024)Mapped to26
The Lifespan of <i>D. melanogaster</i> Depends on the Function of the <i>Gagr</i> Gene, a Domesticated <i>gag</i> Gene of Drosophila LTR Retrotransposons.Balakireva Y., Nikitina M., Makhnovskii P., Kukushkina I., Kuzmin I., Kim A., Nefedova L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCInsects 15:68-68 (2024)Mapped to99+
Recent trends in insect gut immunity.Khan S.A., Kojour M.A.M., Han Y.S.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCFront Immunol 14:1272143-1272143 (2023)Mapped to99+
Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in Drosophila.He J., Han S., Wang Y., Kang Q., Wang X., Su Y., Li Y., Liu Y., Cai H., Xiu M.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCBiomed Pharmacother 169:115906-115906 (2023)Mapped to28
A <i>Drosophila melanogaster</i> model shows that fast growing <i>Metarhizium</i> species are the deadliest despite eliciting a strong immune response.Wang J.B., Lu H.L., Sheng H., St Leger R.J.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCVirulence 14:2275493-2275493 (2023)Mapped to29
<i>Drosophila</i> Gut Immune Pathway Suppresses Host Development-Promoting Effects of Acetic Acid Bacteria.Lee J., Song X., Hyun B., Jeon C.O., Hyun S.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCMol Cells 46:637-653 (2023)Mapped to99+
Immunometabolic regulation during the presence of microorganisms and parasitoids in insects.Li S., Wang J., Tian X., Toufeeq S., Huang W.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCFront Immunol 14:905467-905467 (2023)Mapped to58
Stilbenoid compounds inhibit NF-kappaB-mediated inflammatory responses in the pii>Drosophilapi/i> intestine.Aalto A.L., Saadabadi A., Lindholm F., Kietz C., Himmelroos E., Marimuthu P., Salo-Ahen O.M.H., Eklund P., Meinander A.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCFront Immunol 14:1253805-1253805 (2023)Mapped to14
Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in Drosophila.Wang L., Lin J., Yang K., Wang W., Lv Y., Zeng X., Zhao Y., Yu J., Pan L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCJ Innate Immun 15:697-708 (2023)Mapped to14
A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan.Xu W., Rustenhoven J., Nelson C.A., Dykstra T., Ferreiro A., Papadopoulos Z., Burnham C.D., Dantas G., Fremont D.H., Kipnis J.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCNeuron 111:3244-3254.e8 (2023)Mapped to19
Heuristic-enabled active machine learning: A case study of predicting essential developmental stage and immune response genes in Drosophila melanogaster.Aromolaran O.T., Isewon I., Adedeji E., Oswald M., Adebiyi E., Koenig R., Oyelade J.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCPLoS One 18:e0288023-e0288023 (2023)Mapped to74
Role of Rab5 early endosomes in regulating <i>Drosophila</i> gut antibacterial response.Joshi M., Viallat-Lieutaud A., Royet J.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCiScience 26:107335-107335 (2023)Mapped to33
Drosophila innate immunity suppresses the survival of xenografted mammalian tumor cells.Aida A., Yuswan K., Kawai Y., Hasegawa K., Nakajima Y.I., Kuranaga E.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCSci Rep 13:12334-12334 (2023)Mapped to24
The NF-kappaB factor Relish is essential for the epithelial defenses protecting against delta-endotoxin dependent effects of Bacillus thuringiensis israelensis infection in the Drosophila model.Mouawad C., Awad M.K., Liegeois S., Ferrandon D., Sanchis-Borja V., El Chamy L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCRes Microbiol 174:104089-104089 (2023)Mapped to16
Steroid hormone regulation of innate immunity in Drosophila melanogaster.Keith S.A.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCPLoS Genet 19:e1010782-e1010782 (2023)Mapped to68
Intake of caffeine containing sugar diet remodels gut microbiota and perturbs Drosophila melanogaster immunity and lifespan.Qush A., Al Khatib H.A., Rachid H., Al-Tamimi H., Al-Eshaq A., Al-Adwi S., Yassine H.M., Kamareddine L.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCMicrobes Infect 25:105149-105149 (2023)Mapped to21
Peptidoglycan recognition in Drosophila is mediated by LysMD3/4.Snee M., Wever J., Guyton J., Beehler-Evans R., Yokoyama C.C., Micchelli C.A.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCJ Biol Chem 299:104758-104758 (2023)Mapped to24
Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan.Onuma T., Yamauchi T., Kosakamoto H., Kadoguchi H., Kuraishi T., Murakami T., Mori H., Miura M., Obata F.View abstractSourceFlyBase: FBgn0035976PubMedEurope PMCPLoS Genet 19:e1010709-e1010709 (2023)Mapped to13