E1BGJ0 · E1BGJ0_BOVIN

  • Protein
    LDL receptor related protein 1
  • Gene
    LRP1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentbasolateral plasma membrane
Cellular Componentearly endosome
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular Functionalpha-2 macroglobulin receptor activity
Molecular Functionapolipoprotein binding
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent protein binding
Molecular Functioncargo receptor activity
Molecular Functionclathrin heavy chain binding
Molecular Functionprotein-containing complex binding
Biological Processamyloid-beta clearance by cellular catabolic process
Biological Processamyloid-beta clearance by transcytosis
Biological Processphagocytosis
Biological Processpositive regulation of endocytosis
Biological Processpositive regulation of lysosomal protein catabolic process
Biological Processpositive regulation of protein localization to plasma membrane
Biological Processreceptor-mediated endocytosis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • LDL receptor related protein 1

Gene names

    • Name
      LRP1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    E1BGJ0

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane4426-4446Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-19
ChainPRO_504210593420-4546
Disulfide bond854↔866
Disulfide bond861↔879
Disulfide bond895↔907
Disulfide bond902↔920
Disulfide bond936↔948
Disulfide bond943↔961
Disulfide bond984↔1002
Disulfide bond996↔1011
Disulfide bond1015↔1027
Disulfide bond1022↔1040
Disulfide bond1082↔1097
Disulfide bond1125↔1140
Disulfide bond2532↔2550
Disulfide bond2566↔2578
Disulfide bond2573↔2591
Disulfide bond2585↔2600
Disulfide bond2605↔2617
Disulfide bond2612↔2630
Disulfide bond2624↔2639
Disulfide bond2673↔2688
Disulfide bond2696↔2708
Disulfide bond2703↔2721
Disulfide bond2715↔2730
Disulfide bond2734↔2746
Disulfide bond2741↔2759
Disulfide bond2818↔2830
Disulfide bond2825↔2843
Disulfide bond2858↔2870
Disulfide bond2912↔2930
Disulfide bond2924↔2939
Disulfide bond2986↔2996
Disulfide bond3334↔3346
Disulfide bond3341↔3359
Disulfide bond3374↔3386
Disulfide bond3381↔3399
Disulfide bond3393↔3408
Disulfide bond3433↔3448
Disulfide bond3536↔3548
Disulfide bond3543↔3561
Disulfide bond3555↔3570
Disulfide bond3575↔3587
Disulfide bond3582↔3600
Disulfide bond3594↔3609
Disulfide bond3613↔3625
Disulfide bond3620↔3638
Disulfide bond3632↔3647
Disulfide bond3654↔3666
Disulfide bond3661↔3679
Disulfide bond3716↔3731
Disulfide bond3749↔3767
Disulfide bond3761↔3776
Disulfide bond4202↔4212
Disulfide bond4238↔4248
Disulfide bond4260↔4269
Disulfide bond4274↔4284
Disulfide bond4310↔4320
Disulfide bond4332↔4341
Disulfide bond4379↔4389
Disulfide bond4401↔4410

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat335-378LDL-receptor class B
Repeat379-422LDL-receptor class B
Repeat571-613LDL-receptor class B
Repeat614-659LDL-receptor class B
Repeat660-710LDL-receptor class B
Repeat711-754LDL-receptor class B
Repeat1309-1355LDL-receptor class B
Repeat1356-1398LDL-receptor class B
Repeat1399-1445LDL-receptor class B
Repeat1446-1490LDL-receptor class B
Repeat1627-1669LDL-receptor class B
Repeat1670-1713LDL-receptor class B
Repeat1714-1753LDL-receptor class B
Repeat1934-1976LDL-receptor class B
Repeat1977-2019LDL-receptor class B
Repeat2020-2063LDL-receptor class B
Repeat2064-2107LDL-receptor class B
Repeat2344-2388LDL-receptor class B
Repeat2389-2431LDL-receptor class B
Domain2982-3017EGF-like
Repeat3069-3113LDL-receptor class B
Repeat3114-3156LDL-receptor class B
Repeat3157-3200LDL-receptor class B
Repeat3201-3243LDL-receptor class B
Repeat3972-4014LDL-receptor class B
Repeat4015-4058LDL-receptor class B
Domain4198-4231EGF-like
Domain4234-4270EGF-like
Domain4271-4303EGF-like
Domain4306-4342EGF-like
Domain4377-4411EGF-like

Sequence similarities

Belongs to the LDLR family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    4,546
  • Mass (Da)
    505,031
  • Last updated
    2024-05-29 v4
  • Checksum
    65CF5AEB077899A9

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAA9T4K2A0AAA9T4K2_BOVINLRP1716

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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