E1BDK7 · E1BDK7_BOVIN

  • Protein
    Zinc phosphodiesterase ELAC protein 2
  • Gene
    ELAC2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

  • Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
    EC:3.1.26.11 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial nucleoid
Cellular Componentmitochondrion
Cellular Componentnucleoplasm
Molecular Function3'-tRNA processing endoribonuclease activity
Molecular Functionmetal ion binding
Biological Processmitochondrial tRNA 3'-end processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Zinc phosphodiesterase ELAC protein 2
  • EC number
  • Alternative names
    • ElaC homolog protein 2
    • Ribonuclease Z 2
    • tRNA 3 endonuclease 2
    • tRNase Z 2

Gene names

    • Name
      ELAC2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    E1BDK7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-19
ChainPRO_500314396620-777Zinc phosphodiesterase ELAC protein 2

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region17-49Disordered
Compositional bias27-42Basic and acidic residues
Domain57-116tRNase Z endonuclease
Domain465-679Metallo-beta-lactamase
Region748-777Disordered

Sequence similarities

Belongs to the RNase Z family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    777
  • Mass (Da)
    86,003
  • Last updated
    2011-11-16 v2
  • Checksum
    7026F87BCB1BF40D
MWALRSLLGLRCAAGRTMSQGPARRPRPPKDPLRHLRTREKRGPSWGPGGPNTVYLQVVAAGGRDAGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVSRLDNIFLTRMHWSNVGGLCGMILTLKETGVPKCVLSGPPQLEKYLEAIKIFSGPLKGIDLAVRPHSAPEYKDETMTVFQIPIHCVGWKARGRDTSLVVAFVCKLHVKKGNFLVLKAKELGLPVGTAAIAPIIAAVKDGKSVTYEGREILPEEICTPPDPGITFIVVECPDEGFIQPLCENTTFRSYQGKADAPVALVVHMAPEHVLLDSRYQQWMERFGPDTEHLVLNETCESVHNLRSHKIQTQLSLIHPGIFPPLAGPRPQEGSATQGVPTVRGQCLLKYQLRPRREWQRDAVLTCDPEEFIAEALELPNFQESVQEYRKTAQDSPEATSSQYPEVVFLGTGSAIPMKIRNVSSTLVNISPDTSLLLDCGEGTFGQLCRHYGDGVDRVLGSLAAVFVSHLHADHHTGLLNILLQRERALASLGRPCHPLLVVAPTQLRTWLQQYHNQCQPLLHHVSVIPAKCLQKGAEVSSPEVERLINLLLETCGLEEFQTCLVRHCKHAFGCALVHMSGWKVVYSGDTMPCEALVQMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAIGVGMRMSAAFIMLTHFSQRYAKIPLFSPDFNEKVGIAFDHMKVSLGDLPTVPRLTAPLKALFAGDLEEMEGRRERRELRQVRAALLAGEDVEPPQKRAPTEHPLSPQSKKARAQ

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0AAA9TE74A0AAA9TE74_BOVINELAC2769
A0AAA9TX62A0AAA9TX62_BOVINELAC2154
A0AAA9TW04A0AAA9TW04_BOVINELAC2153

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias27-42Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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