E1AQY3 · PAMT_CAPAN

Function

function

Involved in the biosynthesis of capsaicinoids natural products, pungent alkaloids synthesized from phenylpropanoid intermediates in the placental tissue of chili pepper fruit acting as repellant on herbivorous mammals and conferring spiciness to hot peppers (PubMed:35858994).
Can transfer an amine from vanillylamine to pyruvate forming vanillin and L-alanine (By similarity).

Catalytic activity

Pathway

Aromatic compound metabolism; phenylpropanoid biosynthesis.

Features

Showing features for binding site.

145950100150200250300350400450
TypeIDPosition(s)Description
Binding site115-116pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site255pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site320-321pyridoxal 5'-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4-aminobutyrate transaminase activity
Molecular Functionadenosylmethionine-8-amino-7-oxononanoate transaminase activity
Molecular Functionpyridoxal phosphate binding
Biological Processbiotin biosynthetic process
Biological Processgamma-aminobutyric acid metabolic process
Biological Processphenylpropanoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Vanillin aminotransferase
  • EC number
  • Alternative names
    • Putative aminotransferase
      (pAMT
      )

Gene names

    • Name
      VAMT
    • ORF names
      T459_08319

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Yidu-Red 201
    • cv. Himo
    • cv. Takanotsume
    • cv. CM334
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Capsiceae > Capsicum

Accessions

  • Primary accession
    E1AQY3
  • Secondary accessions
    • A0A125SQB7
    • A0A3T0ZHJ7

Proteomes

Genome annotation databases

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant210in strain: cv. Himo and cv. Takanotsume; altered activity leading to reduced pungency of sweeter fruits producing preferentially capsinoids over capsaicinoids
Natural variant259in strain: cv. Himo; altered activity leading to reduced pungency of sweeter fruits producing preferentially capsinoids over capsaicinoids
Natural variant377in strain: cv. Himo and cv. Takanotsume; altered activity leading to reduced pungency of sweeter fruits producing preferentially capsinoids over capsaicinoids
Natural variant384in strain: cv. Himo and cv. Takanotsume; altered activity leading to reduced pungency of sweeter fruits producing preferentially capsinoids over capsaicinoids

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 4 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004589071-459Vanillin aminotransferase
Modified residue284N6-(pyridoxal phosphate)lysine

Expression

Tissue specificity

Confined to the placenta of green fruits at high levels (PubMed:35858994).
Barely detectable in the pericarp and seeds as well as in the placenta of mature fruits (PubMed:35858994).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil430-457

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    459
  • Mass (Da)
    50,728
  • Last updated
    2010-11-02 v1
  • Checksum
    887155DF888C82D4
MANITNEFMGHDMLAPFTAGWQSDMEPLVIEKSEGSYVYDINGKKYLDTLSGLWCTTLGGSETRLVEAANKQLNTLPFYHSFWNRTTKPSLDLAKELLNMFTANKMAKVFFTNSGSEANDTQVKLVWYYNNALGRPQKKKIIARAKAYHGSTYISAGLSGLPPMHQKFDLPPPFVLHTECPHYWAYHLPGETEEEFSTRLANNLESLILNEGPETVAAFIAEPVLGAAGVILPPATYFDKVQAILRKHDILFIADEVVCGFGRLGTMFGSDKYNIKPDLVSVAKALSSGYMPIAAVLVSQKISSVILSESNKIGAFCHGFTYSGHPVACAVALEALKIYKERNITEVVNKISQKFQEGLKAFADSPIIGEIRGTGLALSTEFVNNKSPNDPFPYEWAVGTYFGAQCAKYGMLVSSTGDHVNMAPPFTLSLEELDELIRIYGKALKDTEKRVEELKSQKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM991733
EMBL· GenBank· DDBJ
ADM13673.1
EMBL· GenBank· DDBJ
mRNA
LC032105
EMBL· GenBank· DDBJ
BAU36961.1
EMBL· GenBank· DDBJ
Genomic DNA
LC423555
EMBL· GenBank· DDBJ
BBG28790.1
EMBL· GenBank· DDBJ
mRNA
AYRZ02000003
EMBL· GenBank· DDBJ
PHT86213.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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