E1ACC5 · E1ACC5_CANLF

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, active site.

1819100200300400500600700800
TypeIDPosition(s)Description
Binding site347Zn2+ (UniProtKB | ChEBI); catalytic
Active site348
Binding site351Zn2+ (UniProtKB | ChEBI); catalytic
Binding site357Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functioncollagen binding
Molecular Functionintegrin binding
Molecular Functionlaminin binding
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Molecular FunctionSH3 domain binding
Biological Processcell-cell adhesion mediated by integrin
Biological Processcell-matrix adhesion
Biological Processcellular response to lipopolysaccharide
Biological Processintegrin-mediated signaling pathway
Biological Processkeratinocyte differentiation
Biological Processmembrane protein ectodomain proteolysis
Biological Processmembrane protein intracellular domain proteolysis
Biological Processmonocyte activation
Biological Processpositive regulation of cell adhesion mediated by integrin
Biological Processpositive regulation of keratinocyte migration
Biological Processpositive regulation of macrophage fusion
Biological Processpositive regulation of protein secretion
Biological Processresponse to calcium ion
Biological Processresponse to hydrogen peroxide
Biological Processresponse to manganese ion
Biological Processresponse to tumor necrosis factor
Biological Processtransforming growth factor beta receptor signaling pathway

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • A disintegrin and metallopeptidase domain 9
    • ADAM metallopeptidase domain 9
    • Disintegrin and metalloproteinase domain 9,transcript variant 1

Gene names

    • Name
      ADAM9
    • Synonyms
      adam9

Organism names

  • Taxonomic identifier
  • Strain
    • Labrador retriever
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis

Accessions

  • Primary accession
    E1ACC5

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane699-718Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_501011330429-819
Disulfide bond365↔370
Disulfide bond473↔493
Disulfide bond664↔673

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain212-406Peptidase M12B
Domain414-501Disintegrin
Domain640-674EGF-like
Region734-819Disordered
Compositional bias739-756Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    819
  • Mass (Da)
    90,805
  • Last updated
    2010-11-02 v1
  • Checksum
    37DF8DDFA764C324
MGSGAGSPFGVFRLQWLLLFGTVGPVLGGARPGFQQTSHLSSYEIITPWRLTRERREAPRPYSEQVSYIIQAEGKEHIIHLERNNDFLPRDFVVYTYNKEGALISDHPDVQNHCHYRGYVEGISNSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHKEPLKCGVSNKDMEKETTNYEEEEPLSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMIRLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIIGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCFCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPFCGNKLVDPGEECDCGTPKECESDPCCEGTTCKLKSSAECAYGDCCKDCWFLPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPRDCFIDVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQDMPVFGIVPAIIQTPSKGTKCWGVDFQLGSDVPDPGMVNEGTRCDNGKICRNFQCVNASVLNYDCDIQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDSGPTYNEKNTALRDGLLVFFFLIVPLIVCAAFVFIKRDQLWRSYFQKKRSQTYESDGKNQAKASRQPVSVPRHVSSVTPPREAPIYANRFPVPTYAAKQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I3NHT4A0A8I3NHT4_CANLFADAM9548
A0A8I3NHM2A0A8I3NHM2_CANLFADAM9766
A0A8I3NHS9A0A8I3NHS9_CANLFADAM9640
A0A8I3NI05A0A8I3NI05_CANLFADAM9771
A0A8I3RWE0A0A8I3RWE0_CANLFADAM9126

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias739-756Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM590630
EMBL· GenBank· DDBJ
ADM48814.1
EMBL· GenBank· DDBJ
mRNA
FR667706
EMBL· GenBank· DDBJ
CBV37337.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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