E0SNQ8 · PUS10_IGNAA
- ProteintRNA pseudouridine synthase Pus10
- Genepus10
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids430 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
Catalytic activity
- uridine54 in tRNA = pseudouridine54 in tRNA
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 253 | Nucleophile | ||||
Sequence: D | ||||||
Binding site | 320 | substrate | ||||
Sequence: Y | ||||||
Binding site | 392 | substrate | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | tRNA binding | |
Molecular Function | tRNA pseudouridine(55) synthase activity | |
Biological Process | tRNA pseudouridine synthesis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA pseudouridine synthase Pus10
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Desulfurococcales > Desulfurococcaceae > Ignisphaera
Accessions
- Primary accessionE0SNQ8
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000407386 | 1-430 | tRNA pseudouridine synthase Pus10 | |||
Sequence: MSIIDIANNILRKYCLCDRCLGRLFASLGRGLSNDERGKAIKIALVLELHKRYLDGDKDSLKQLVELSPNIGPIAVNLIKNLGIEIEYTPRTCFICDNKINDIIDTYSQRIADIINERHINSFVLGIRGVTSYIRKEESIANEFKLLYWENIKRELKREIGKKIQMMTNAKVDFLNPEAMIIIDIDRDRIYIESPSLLIYGRYWKLGRMISQNIWLTKNGVKKYPLSIEEIAKMLVKDGFGDDVVLHIAGREDVDVRTLGSGRPFVLEIKRPRKRNIDIKDIENRLNSISRWLKFELNMFVDRDFVSRVKKGCRTSYKIYRAIVVADRDIGIEDIKRLEEFFRDRIIEQRTPTRVLRRKKDVLRRRKVFEIKTRVISPRVFEALIKCEGGLYVKELISGDNGRTVPSFSSVLNANTLCLTLDALYVHEYI |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length430
- Mass (Da)50,020
- Last updated2010-11-02 v1
- ChecksumD7127DF93B473F90
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002098 EMBL· GenBank· DDBJ | ADM27854.1 EMBL· GenBank· DDBJ | Genomic DNA |