E0CXR8 · E0CXR8_MOUSE
- ProteinPar-3 family cell polarity regulator
- GenePard3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids990 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | bicellular tight junction | |
Cellular Component | endomembrane system |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Glires (Rodents and rabbits) > Rodentia (rodent) > Myomorpha (mice and others) > Muroidea > Muridae > Murinae > Mus (mice) > Mus
Accessions
- Primary accessionE0CXR8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 81-101 | Disordered | ||||
Sequence: EQDPHHGGDGTSASSTGTQSP | ||||||
Region | 143-262 | Disordered | ||||
Sequence: SSDPALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDPSSWSNQFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLEN | ||||||
Compositional bias | 146-187 | Polar residues | ||||
Sequence: PALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGS | ||||||
Compositional bias | 188-202 | Basic and acidic residues | ||||
Sequence: PKTCDRKKDENYRSL | ||||||
Compositional bias | 203-224 | Polar residues | ||||
Sequence: PRDPSSWSNQFQRDNARSSLSA | ||||||
Domain | 271-347 | PDZ | ||||
Sequence: MVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQA | ||||||
Region | 369-388 | Disordered | ||||
Sequence: LSQREKNNYSPGRFSPDSHC | ||||||
Region | 397-441 | Disordered | ||||
Sequence: NAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPAAPALAPPS | ||||||
Domain | 461-546 | PDZ | ||||
Sequence: NIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFR | ||||||
Domain | 590-665 | PDZ | ||||
Sequence: EVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRS | ||||||
Region | 831-853 | Disordered | ||||
Sequence: TVDDQRAGSPSRDVGPSLGLKKS | ||||||
Region | 898-990 | Disordered | ||||
Sequence: SYDKPMVDDDDEGMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKGMLKGLGDMF | ||||||
Compositional bias | 925-942 | Polar residues | ||||
Sequence: GRESVSTSSDQPSYSLER | ||||||
Compositional bias | 944-982 | Basic and acidic residues | ||||
Sequence: MNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKGM |
Sequence similarities
Belongs to the PAR3 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length990
- Mass (Da)108,874
- Last updated2010-10-05 v1
- ChecksumAB304EE6BBF19499
Computationally mapped potential isoform sequences
There are 21 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q99NH2 | PARD3_MOUSE | Pard3 | 1333 | ||
F6TB42 | F6TB42_MOUSE | Pard3 | 116 | ||
E9PYJ2 | E9PYJ2_MOUSE | Pard3 | 741 | ||
A0A0R4J1Y4 | A0A0R4J1Y4_MOUSE | Pard3 | 896 | ||
F6T4Y3 | F6T4Y3_MOUSE | Pard3 | 102 | ||
A0A5F8MPS2 | A0A5F8MPS2_MOUSE | Pard3 | 54 | ||
F6URI7 | F6URI7_MOUSE | Pard3 | 269 | ||
B7ZNY3 | B7ZNY3_MOUSE | Pard3 | 1319 | ||
F6UGU7 | F6UGU7_MOUSE | Pard3 | 919 | ||
Q4JJC0 | Q4JJC0_MOUSE | Pard3 | 422 | ||
F6S7Z1 | F6S7Z1_MOUSE | Pard3 | 1324 | ||
G3XA13 | G3XA13_MOUSE | Pard3 | 1333 | ||
F6TSJ9 | F6TSJ9_MOUSE | Pard3 | 984 | ||
E0CZ83 | E0CZ83_MOUSE | Pard3 | 1094 | ||
E0CZE2 | E0CZE2_MOUSE | Pard3 | 1024 | ||
E0CX45 | E0CX45_MOUSE | Pard3 | 943 | ||
A5D6P2 | A5D6P2_MOUSE | Pard3 | 1334 | ||
E0CXD3 | E0CXD3_MOUSE | Pard3 | 59 | ||
E0CXL4 | E0CXL4_MOUSE | Pard3 | 1289 | ||
E0CY24 | E0CY24_MOUSE | Pard3 | 1247 | ||
E0CYB6 | E0CYB6_MOUSE | Pard3 | 44 |
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 146-187 | Polar residues | ||||
Sequence: PALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGS | ||||||
Compositional bias | 188-202 | Basic and acidic residues | ||||
Sequence: PKTCDRKKDENYRSL | ||||||
Compositional bias | 203-224 | Polar residues | ||||
Sequence: PRDPSSWSNQFQRDNARSSLSA | ||||||
Compositional bias | 925-942 | Polar residues | ||||
Sequence: GRESVSTSSDQPSYSLER | ||||||
Compositional bias | 944-982 | Basic and acidic residues | ||||
Sequence: MNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKGM | ||||||
Non-terminal residue | 990 | |||||
Sequence: F |
Keywords
- Technical term