Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene.Walther T., Balschun D., Voigt J.P., Fink H., Zuschratter W., Birchmeier C., Ganten D., Bader M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCJ Biol Chem 273:11867-11873 (1998)Mapped to6
Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice.Rooney R.J., Daniels R.R., Jenkins N.A., Gilbert D.J., Rothammer K., Morris S.W., Higgs D.R., Copeland N.G.CategoryFunctionSourceMGI: 96918PubMedEurope PMCMamm. Genome 9:320-323 (1998)Cited in2Mapped to14
Mas oncogene signaling and transformation require the small GTP-binding protein Rac.Zohn I.E., Symons M., Chrzanowska-Wodnicka M., Westwick J.K., Der C.J.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCMol Cell Biol 18:1225-1235 (1998)Mapped to6
ACE2 pathway regulates thermogenesis and energy metabolism.Cao X., Shi T.T., Zhang C.H., Jin W.Z., Song L.N., Zhang Y.C., Liu J.Y., Yang F.Y., Rotimi C.N.[...], Yang J.K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCElife 11:e72266-e72266 (2022)Mapped to18
Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis.Zaidan I., Tavares L.P., Sugimoto M.A., Lima K.M., Negreiros-Lima G.L., Teixeira L.C., Miranda T.C., Valiate B.V., Cramer A.[...], Sousa L.P.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCJCI Insight 7:e147819-e147819 (2022)Mapped to10
Early onset of aging phenotype in vascular repair by Mas receptor deficiency.Vasam G., S S.J., Miyat S.Y., Adam H., Jarajapu Y.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCGeroscience 44:311-327 (2022)Mapped to6
Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle.Rivera J.C., Abrigo J., Tacchi F., Simon F., Brandan E., Santos R.A., Bader M., Chiong M., Cabello-Verrugio C.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCInt J Mol Sci 21:E9344-E9344 (2020)Mapped to7
Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism.Song L.N., Liu J.Y., Shi T.T., Zhang Y.C., Xin Z., Cao X., Yang J.K.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCFASEB J 34:16291-16306 (2020)Mapped to13
Angiotensin-(1-7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice.Jarve A., Qadri F., Todiras M., Schmolke S., Alenina N., Bader M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCFront Physiol 11:203-203 (2020)Mapped to6
Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor.Vargas-Castillo A., Tobon-Cornejo S., Del Valle-Mondragon L., Torre-Villalvazo I., Schcolnik-Cabrera A., Guevara-Cruz M., Pichardo-Ontiveros E., Fuentes-Romero R., Bader M.[...], Tovar A.R.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCMetabolism 103:154048-154048 (2020)Mapped to11
Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice.Nozato S., Yamamoto K., Takeshita H., Nozato Y., Imaizumi Y., Fujimoto T., Yokoyama S., Nagasawa M., Takeda M.[...], Rakugi H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCClin Sci (Lond) 133:2005-2018 (2019)Mapped to12
The role of receptor MAS in microglia-driven retinal vascular development.Foulquier S., Caolo V., Swennen G., Milanova I., Reinhold S., Recarti C., Alenina N., Bader M., Steckelings U.M.[...], Unger T.View abstractCategoriesFunction, ExpressionSourceMGI: 96918PubMedEurope PMCAngiogenesis 22:481-489 (2019)Mapped to7
Mas receptor deficiency augments angiotensin II-induced atherosclerosis and aortic aneurysm ruptures in hypercholesterolemic male mice.Stegbauer J., Thatcher S.E., Yang G., Bottermann K., Rump L.C., Daugherty A., Cassis L.A.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCJ Vasc Surg 70:1658-1668.e1 (2019)Mapped to28
Reduced disease severity following therapeutic treatment with angiotensin 1-7 in a mouse model of multiple sclerosis.Lund B.T., Stone R., Levy A.M., Lee S., Amundson E., Kashani N., Rodgers K.E., Kelland E.E.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCNeurobiol Dis 127:87-100 (2019)Mapped to6
Angiotensin-(1-7) Receptor Mas in Hemodynamic and Thermoregulatory Dysfunction After High-Level Spinal Cord Injury in Mice: A Pilot Study.Jarve A., Todiras M., Kny M., Fischer F.I., Kraemer J.F., Wessel N., Plehm R., Fielitz J., Alenina N., Bader M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCFront Physiol 9:1930-1930 (2018)Mapped to6
Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.Klempin F., Mosienko V., Matthes S., Villela D.C., Todiras M., Penninger J.M., Bader M., Santos R.A.S., Alenina N.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCCell Mol Life Sci 75:3625-3634 (2018)Mapped to12
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.Burghi V., Fernandez N.C., Gandola Y.B., Piazza V.G., Quiroga D.T., Guilhen Mario E., Felix Braga J., Bader M., Santos R.A.S.[...], Munoz M.C.View abstractCategoriesFunction, Expression, Subcellular LocationSourceMGI: 96918PubMedEurope PMCPLoS One 12:e0183278-e0183278 (2017)Mapped to6
Mas receptor is involved in the estrogen-receptor induced nitric oxide- dependent vasorelaxation.Sobrino A., Vallejo S., Novella S., Lazaro-Franco M., Mompeon A., Bueno-Beti C., Walther T., Sanchez-Ferrer C., Peiro C., Hermenegildo C.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCBiochem Pharmacol 129:67-72 (2017)Mapped to6
Reversal of Bone Marrow Mobilopathy and Enhanced Vascular Repair by Angiotensin-(1-7) in Diabetes.Vasam G., Joshi S., Thatcher S.E., Bartelmez S.H., Cassis L.A., Jarajapu Y.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCDiabetes 66:505-518 (2017)Mapped to12
Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.Magalhaes G.S., Rodrigues-Machado M.G., Motta-Santos D., Alenina N., Bader M., Santos R.A., Barcelos L.S., Campagnole-Santos M.J.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCAm J Physiol Lung Cell Mol Physiol 311:L1141-L1148 (2016)Mapped to7
The Angiotensin-(1-7)/Mas Axis Improves Pancreatic beta-Cell Function in Vitro and in Vivo.Sahr A., Wolke C., Maczewsky J., Krippeit-Drews P., Tetzner A., Drews G., Venz S., Gurtler S., van den Brandt J.[...], Lendeckel U.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCEndocrinology 157:4677-4690 (2016)Mapped to7
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis.Callera G.E., Antunes T.T., Correa J.W., Moorman D., Gutsol A., He Y., Cat A.N., Briones A.M., Montezano A.C.[...], Touyz R.M.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCBiosci Rep 36:e00398-e00398 (2016)Mapped to23
Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury.Ali Q., Dhande I., Samuel P., Hussain T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96918PubMedEurope PMCJ Renin Angiotensin Aldosterone Syst 17:1470320316661871-1470320316661871 (2016)Mapped to13
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas.Morales M.G., Abrigo J., Acuna M.J., Santos R.A., Bader M., Brandan E., Simon F., Olguin H., Cabrera D., Cabello-Verrugio C.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCDis Model Mech 9:441-449 (2016)Mapped to6
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.Wang L., de Kloet A.D., Pati D., Hiller H., Smith J.A., Pioquinto D.J., Ludin J.A., Oh S.P., Katovich M.J.[...], Krause E.G.View abstractCategoryFunctionSourceMGI: 96918PubMedEurope PMCNeuropharmacology 105:114-123 (2016)Mapped to13