E0AG96 · E0AG96_9GOBI

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    ND4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 11
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Gobiaria > Gobiiformes > Gobioidei > Gobiidae > Sicydiinae > Stiphodon

Accessions

  • Primary accession
    E0AG96

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane23-42Helical
Transmembrane62-81Helical
Transmembrane93-111Helical
Transmembrane146-168Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-110NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain113-181NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    195
  • Mass (Da)
    21,720
  • Last updated
    2010-10-05 v1
  • Checksum
    ACDACC3AE282C955
MLKILIPTIMLVPTTWLAPAKTIWPTALMHSLIIALMSLMWLHSSGETGWSSLNHFMALDPLSTPLLVLTCWLLPLMILASQNHTAGEPMNRQRMYISLLTSLQIFLIMAFSATEVILFYIMFEATLVPTLLLITRWGNQAERLNAGTYFLFYTLAGSLPLLVALLLLQNTTGTLSLLTLQYAPALPMLTTGDKI

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue195

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HQ000054
EMBL· GenBank· DDBJ
ADL14620.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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