E0ADF8 · E0ADF8_9FLAV

  • Protein
    RNA-directed RNA polymerase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthost cell membrane
Cellular Componentmembrane
Molecular FunctionATP hydrolysis activity
Molecular Functionnucleotide binding
Molecular Functionpeptidase activity
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Biological Processfusion of virus membrane with host endosome membrane
Biological Processproteolysis
Biological Processviral RNA genome replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA-directed RNA polymerase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 1855
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Kitrinoviricota > Flasuviricetes > Amarillovirales > Flaviviridae > Pegivirus > Pegivirus hominis

Accessions

  • Primary accession
    E0ADF8

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain73-187RdRp catalytic

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    242
  • Mass (Da)
    26,877
  • Last updated
    2010-10-05 v1
  • Checksum
    3332E171E63AC2C0
TVKKEVFYRDRKEEKAPRLIVFPPLDFRVAEKMIMGDPGRVAKGILGDAYAFQYTPNQRVKKMVEMWGSKKTPCAICVDAKCFDSSINLEDVELETELYALASDNPEQVRALGRYYAEGPMVSPEEVPLGHRFCRSSGVLTTSSSNCITCYIKVSAACARIGLKGVSLLIAGDDCLIICERPICDPCEALGVALRSYGYNCEPSYHASLDTAPFCSTWLAECNANGSRHFFLTTDFRRPLAR

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue242

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM626494
EMBL· GenBank· DDBJ
ADL29714.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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