D9QET8 · D9QET8_CORP2
- ProteinProtein translocase subunit SecA
- GenesecA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids847 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Catalytic activity
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Biological Process | intracellular protein transmembrane transport | |
Biological Process | protein import | |
Biological Process | protein targeting |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein translocase subunit SecA
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionD9QET8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Note: Distribution is 50-50.
Keywords
- Cellular component
Interaction
Subunit
Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-614 | SecA family profile | ||||
Sequence: MFGLSKMLRVGEGRAVKRLKKIAEDVIDLEPQFSELSDDELKAKTKEFQDRIAAGETVDDLLLEAFAVAREASWRVLGQKHYLVQVMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLEVGVILANMQPTERRAAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQITPRLTRDIHFEVDERKRTVGIKEEGVAYVEDQLGIENLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVLIVDDFTGRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNYFRLYDKLAGMTGTAETEASELHQIYKLDVIPIPTNRDNQREDMTDLVYKTQEAKFAAVVDDIAERVAKGQPVLVGTTSVERSEYLSRLLQRRGVKHSVLNAKFHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPDIIADINLRERGLDPVETPEEYEAAWDEELAKVKNRGERLAEEVRKAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGTTRFYLSMRDELMVRFVGQSMENMMNRLNVPDDVPIE | ||||||
Domain | 87-245 | Helicase ATP-binding | ||||
Sequence: MGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLEVGVILANMQPTERRAAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQITPRLT | ||||||
Domain | 402-619 | Helicase C-terminal | ||||
Sequence: DMTDLVYKTQEAKFAAVVDDIAERVAKGQPVLVGTTSVERSEYLSRLLQRRGVKHSVLNAKFHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPDIIADINLRERGLDPVETPEEYEAAWDEELAKVKNRGERLAEEVRKAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGTTRFYLSMRDELMVRFVGQSMENMMNRLNVPDDVPIEAKMVT |
Sequence similarities
Belongs to the SecA family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length847
- Mass (Da)95,526
- Last updated2010-10-05 v1
- Checksum8AB6829E69144D53
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001829 EMBL· GenBank· DDBJ | ADL10011.1 EMBL· GenBank· DDBJ | Genomic DNA |