D9QET8 · D9QET8_CORP2

Function

function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

Catalytic activity

  • ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.
    EC:7.4.2.8 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

1847100200300400500600700800
TypeIDPosition(s)Description
Binding site85ATP (UniProtKB | ChEBI)
Binding site103-107ATP (UniProtKB | ChEBI)
Binding site492ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Biological Processintracellular protein transmembrane transport
Biological Processprotein import
Biological Processprotein targeting

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein translocase subunit SecA
  • EC number

Gene names

    • Name
      secA
    • ORF names
      CPC231_02620

Organism names

Accessions

  • Primary accession
    D9QET8

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm
Note: Distribution is 50-50.

Keywords

Interaction

Subunit

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-614SecA family profile
Domain87-245Helicase ATP-binding
Domain402-619Helicase C-terminal

Sequence similarities

Belongs to the SecA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    847
  • Mass (Da)
    95,526
  • Last updated
    2010-10-05 v1
  • Checksum
    8AB6829E69144D53
MFGLSKMLRVGEGRAVKRLKKIAEDVIDLEPQFSELSDDELKAKTKEFQDRIAAGETVDDLLLEAFAVAREASWRVLGQKHYLVQVMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLEVGVILANMQPTERRAAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQITPRLTRDIHFEVDERKRTVGIKEEGVAYVEDQLGIENLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVLIVDDFTGRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNYFRLYDKLAGMTGTAETEASELHQIYKLDVIPIPTNRDNQREDMTDLVYKTQEAKFAAVVDDIAERVAKGQPVLVGTTSVERSEYLSRLLQRRGVKHSVLNAKFHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPDIIADINLRERGLDPVETPEEYEAAWDEELAKVKNRGERLAEEVRKAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGTTRFYLSMRDELMVRFVGQSMENMMNRLNVPDDVPIEAKMVTNSIKGAQASVENQNFEMRKNVLKYDEVMNEQRKVIYSERREILESADIAENIQKMIDDTIGAYVDGATANGYVEDWDLDALWNALESLYGPSMQAQELIDGTEYGSAGELSESDLRAAVLEDAHKQYAELEENVSAIGGEAQMRNIERMVILPVIDQKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNAMKDGIKEETVRQLFLLRKQFQAPAVDETVEA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001829
EMBL· GenBank· DDBJ
ADL10011.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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