D9Q9U2 · D9Q9U2_CORP2
- ProteinTranscription termination factor Rho
- Generho
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids728 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent activity, acting on RNA | |
Molecular Function | helicase activity | |
Molecular Function | RNA binding | |
Biological Process | DNA-templated transcription termination |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranscription termination factor Rho
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium
Accessions
- Primary accessionD9Q9U2
Proteomes
Interaction
Subunit
Homohexamer. The homohexamer assembles into an open ring structure.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-24 | Disordered | ||||
Sequence: MTSFTSGKGDERTSVTTTDNGAQR | ||||||
Region | 61-334 | Disordered | ||||
Sequence: AQGGKAAQSGHSAAPAAKRNARAQAAPKAEKDSAPVENSVPEVSKEQQEKADQVPAKESKSRRRRVLKTTGTMDSTHETASSEPISQESSPAEEEKPRRRRVTRRVEVSSEKRDPAENSPQDKTDTPSESNDGVARVSENGDAEDENRYESRSAARRARRNRARREHREDRQTSQREDNHAEGDRSSNDEEQRKEASVDNVKATGRREASEQQAADQPQTRETREGSENEHPRQRNGRHHERGERGDRNRRNRRNRRGRDRDDHRDNSNIEPRE | ||||||
Compositional bias | 103-131 | Basic and acidic residues | ||||
Sequence: VSKEQQEKADQVPAKESKSRRRRVLKTTG | ||||||
Compositional bias | 132-148 | Polar residues | ||||
Sequence: TMDSTHETASSEPISQE | ||||||
Compositional bias | 149-180 | Basic and acidic residues | ||||
Sequence: SSPAEEEKPRRRRVTRRVEVSSEKRDPAENSP | ||||||
Compositional bias | 181-195 | Polar residues | ||||
Sequence: QDKTDTPSESNDGVA | ||||||
Compositional bias | 198-216 | Basic and acidic residues | ||||
Sequence: SENGDAEDENRYESRSAAR | ||||||
Compositional bias | 225-266 | Basic and acidic residues | ||||
Sequence: REHREDRQTSQREDNHAEGDRSSNDEEQRKEASVDNVKATGR | ||||||
Compositional bias | 281-308 | Basic and acidic residues | ||||
Sequence: RETREGSENEHPRQRNGRHHERGERGDR | ||||||
Compositional bias | 319-333 | Basic and acidic residues | ||||
Sequence: RDRDDHRDNSNIEPR | ||||||
Domain | 338-425 | Rho RNA-BD | ||||
Sequence: LQNIAGILDIVDSNVAFVRTSGYHAGSADVYVNNQMIRRLGLRAGDAITGQVRMNGDNNHGGHHGHNRGRNRQKYNPLVRVESVNGMS |
Sequence similarities
Belongs to the Rho family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length728
- Mass (Da)80,479
- Last updated2023-06-28 v2
- Checksum14C18C110D291653
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 103-131 | Basic and acidic residues | ||||
Sequence: VSKEQQEKADQVPAKESKSRRRRVLKTTG | ||||||
Compositional bias | 132-148 | Polar residues | ||||
Sequence: TMDSTHETASSEPISQE | ||||||
Compositional bias | 149-180 | Basic and acidic residues | ||||
Sequence: SSPAEEEKPRRRRVTRRVEVSSEKRDPAENSP | ||||||
Compositional bias | 181-195 | Polar residues | ||||
Sequence: QDKTDTPSESNDGVA | ||||||
Compositional bias | 198-216 | Basic and acidic residues | ||||
Sequence: SENGDAEDENRYESRSAAR | ||||||
Compositional bias | 225-266 | Basic and acidic residues | ||||
Sequence: REHREDRQTSQREDNHAEGDRSSNDEEQRKEASVDNVKATGR | ||||||
Compositional bias | 281-308 | Basic and acidic residues | ||||
Sequence: RETREGSENEHPRQRNGRHHERGERGDR | ||||||
Compositional bias | 319-333 | Basic and acidic residues | ||||
Sequence: RDRDDHRDNSNIEPR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001829 EMBL· GenBank· DDBJ | ADL10318.2 EMBL· GenBank· DDBJ | Genomic DNA |