D9Q9U2 · D9Q9U2_CORP2

Function

function

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

1728100200300400500600700
TypeIDPosition(s)Description
Binding site468-473ATP (UniProtKB | ChEBI)
Binding site480-485ATP (UniProtKB | ChEBI)
Binding site511ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent activity, acting on RNA
Molecular Functionhelicase activity
Molecular FunctionRNA binding
Biological ProcessDNA-templated transcription termination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Transcription termination factor Rho
  • EC number
  • Alternative names
    • ATP-dependent helicase Rho

Gene names

    • Name
      rho
    • ORF names
      CPC231_04210

Organism names

Accessions

  • Primary accession
    D9Q9U2

Proteomes

Interaction

Subunit

Homohexamer. The homohexamer assembles into an open ring structure.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-24Disordered
Region61-334Disordered
Compositional bias103-131Basic and acidic residues
Compositional bias132-148Polar residues
Compositional bias149-180Basic and acidic residues
Compositional bias181-195Polar residues
Compositional bias198-216Basic and acidic residues
Compositional bias225-266Basic and acidic residues
Compositional bias281-308Basic and acidic residues
Compositional bias319-333Basic and acidic residues
Domain338-425Rho RNA-BD

Sequence similarities

Belongs to the Rho family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    728
  • Mass (Da)
    80,479
  • Last updated
    2023-06-28 v2
  • Checksum
    14C18C110D291653
MTSFTSGKGDERTSVTTTDNGAQRNLAALRLPELRKIAAEMGLKGTSALRKGDLIAAISGAQGGKAAQSGHSAAPAAKRNARAQAAPKAEKDSAPVENSVPEVSKEQQEKADQVPAKESKSRRRRVLKTTGTMDSTHETASSEPISQESSPAEEEKPRRRRVTRRVEVSSEKRDPAENSPQDKTDTPSESNDGVARVSENGDAEDENRYESRSAARRARRNRARREHREDRQTSQREDNHAEGDRSSNDEEQRKEASVDNVKATGRREASEQQAADQPQTRETREGSENEHPRQRNGRHHERGERGDRNRRNRRNRRGRDRDDHRDNSNIEPREDEVLQNIAGILDIVDSNVAFVRTSGYHAGSADVYVNNQMIRRLGLRAGDAITGQVRMNGDNNHGGHHGHNRGRNRQKYNPLVRVESVNGMSVEEAKARPDFSKLTPLYPNQRLRLETEPKILTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQNIANAIATNNPECYLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSEHTAVAELAIERAKRLVEQGQDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSNALYPPKRFLGAARNIENGGSLTIIATAMVETGSAGDTVIFEEFKGTGNAELKLDRKISERRVFPAVDVNPSGTRKDELLLVPEEARIMHKLRRILAALDNQQAIDLLIKQLKKTKSNGEFLMQIASSAPMAADAEEE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias103-131Basic and acidic residues
Compositional bias132-148Polar residues
Compositional bias149-180Basic and acidic residues
Compositional bias181-195Polar residues
Compositional bias198-216Basic and acidic residues
Compositional bias225-266Basic and acidic residues
Compositional bias281-308Basic and acidic residues
Compositional bias319-333Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001829
EMBL· GenBank· DDBJ
ADL10318.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp