D9MNA7 · D9MNA7_DANRE

Function

Catalytic activity

Features

Showing features for binding site, active site, site.

110641002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site558Mg2+ (UniProtKB | ChEBI)
Binding site586-593ATP (UniProtKB | ChEBI)
Binding site613ATP (UniProtKB | ChEBI)
Binding site661-667ATP (UniProtKB | ChEBI)
Active site803Proton acceptor
Binding site807ATP (UniProtKB | ChEBI)
Binding site808Mg2+ (UniProtKB | ChEBI)
Binding site821Mg2+ (UniProtKB | ChEBI)
Site947Important for interaction with phosphotyrosine-binding proteins

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functiontransmembrane receptor protein tyrosine kinase activity
Biological Processangiogenesis
Biological Processangiogenesis involved in coronary vascular morphogenesis
Biological Processblood vessel morphogenesis
Biological Processcerebellum vasculature development
Biological Processcoronary vasculature development
Biological Processembryonic neurocranium morphogenesis
Biological Processglomerular mesangium development
Biological Processhematopoietic stem cell differentiation
Biological Processneural crest cell migration
Biological Processpericyte cell differentiation
Biological Processplatelet-derived growth factor receptor-beta signaling pathway
Biological Processpositive regulation of epithelial cell proliferation
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processtissue regeneration
Biological Processvascular associated smooth muscle cell development
Biological Processwound healing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      pdgfrb
    • Synonyms
      pdgfrb2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    D9MNA7

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane511-535Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain1-109Ig-like
Domain201-294Ig-like
Domain307-392Ig-like
Domain579-939Protein kinase
Region966-1064Disordered
Compositional bias972-986Pro residues
Compositional bias1019-1037Polar residues
Compositional bias1039-1055Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,064
  • Mass (Da)
    119,715
  • Last updated
    2010-10-05 v1
  • Checksum
    239D33585AC8247C
MKSSTISRIHFLFTAITTGLVLLCLGTSGLELSPSAPQIILSINSSSSITCSGWSNVTWRFRRDENIPDFRTEELSASSSVLHLEQVTWRHTGVYVCTEKKTNESREVAVFVPDPDVWFLENEHVMVTKTREEGTIPCLVTNPSINVTLYERDTEMAVEGSYNPSVGYSAALDDRTYICKGELNGEEKESDLFYVFSILAPEALDPYINASKTVLKQGETLNVNCTVHGVELVFFSWDFPNKDMGGIEPLTDVLSSMSMRSCLNITDVSLDRSGQYVCHVHEGVQDQRASASINITVLEKGFVSLTPPLDRNISAQLGENVELKVEIEAYPKPTVQWRKDGAVIRGHSMREEHETRFVSTLTLVRTRLQQMGLYKVTVQNEDALKEMIFDLEVKVPPQITELSDHHLPEKKHAVTCVAEGVPKPSIQWFSCDSMTRCSNRSAVWSPLVEDPESVTIQTNVTYNSTRKIHQVLSQVTLVRPQLLTIRCEASNERGARARDIRLVNSTLFSQVAVLAAVLALVVIVIISIIILIAVWRKKPRYEIRWKVIESVSLDGHEYIYVDPIHLPYDLAWEMPRDSLVLGRTLGSGAFGRVVEATAYGLGISQSATKVAVKMLKSTARRSETQALMSELKIMSHLGPHINIVNLLGACTKQGPLYLVTEYCRYGDLVDYLHRNKHSFLQNFADKNHIAHGTQICNDSDSGKEYVSFGSECDGGYMDMTKDEQTEYVPMQELADTIKYADIQPSPYESPYQQEIYQEQGPRVDHPLVISDSPVLSYTDLVGFSYQVAQGMEFLASKNCVHRDLAARNVLICEGKLAKICDFGLARDIMHDNNYISKGSTFLPLKWMAPESIFHNLYTTLSDVWSYGILLWEIFTLGGTPYPDLPMNELFYSALKRGYRMAKPSYASDEIYEVMRKCWDEKYEKRPEFSFLVHTMGNMLSDAYKKKYSQVNDSFLKSDHPAVARMKPRVPSPFPGAFSPQSPTPELTPRPQIDGEAPHNEYIIPIPDPKPEEETQDEPTAAEIPSSSFSSDEETVSMEAPSTEPEREELLTEHFGSPEVEESFL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9QKL5A0A8M9QKL5_DANREpdgfrb1072

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias972-986Pro residues
Compositional bias1019-1037Polar residues
Compositional bias1039-1055Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HM439112
EMBL· GenBank· DDBJ
ADI61972.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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