D7PC82 · D7PC82_MONDO
- ProteinATP-binding cassette transporter protein
- GeneABCB4
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1278 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Metatheria > Didelphimorphia > Didelphidae > Monodelphis
Accessions
- Primary accessionD7PC82
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 53-76 | Helical | ||||
Sequence: LFMVLGTVMAIAHGSGLPLMMIVF | ||||||
Transmembrane | 115-140 | Helical | ||||
Sequence: AYYYSGLGGGVLIAAYIQVSFWTLAA | ||||||
Transmembrane | 190-209 | Helical | ||||
Sequence: VGMFFQAVATFFAGFIVGFI | ||||||
Transmembrane | 215-233 | Helical | ||||
Sequence: TLVIMAISPILGLSAAVWA | ||||||
Transmembrane | 295-316 | Helical | ||||
Sequence: ANISMGIAFLLIYASYALAFWY | ||||||
Transmembrane | 328-349 | Helical | ||||
Sequence: IGNALTVFFSILIGAFSVGQAA | ||||||
Transmembrane | 707-731 | Helical | ||||
Sequence: WPYFVVGTLCAIVNGALQPAFSIIF | ||||||
Transmembrane | 751-770 | Helical | ||||
Sequence: NMFSLLFLGLGIISFFTFFL | ||||||
Transmembrane | 857-878 | Helical | ||||
Sequence: LLLLSVVPIIAVSGIIEIKMLA | ||||||
Transmembrane | 933-952 | Helical | ||||
Sequence: AHIYGITFSISQAFMYFSYA | ||||||
Transmembrane | 972-993 | Helical | ||||
Sequence: VILVFSAIVFGAMALGHASSFA |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-33 | Disordered | ||||
Sequence: MDREEERNGTAGSSEGDFELATTSNQQDRKKMK | ||||||
Domain | 56-357 | ABC transmembrane type-1 | ||||
Sequence: VLGTVMAIAHGSGLPLMMIVFGEMTDSFVNTAGNFSFPVNFSLAMLNPARILEEEMTRYAYYYSGLGGGVLIAAYIQVSFWTLAAGRQIKKIRQKFFHAVLQQEIGWFDVNDTTELNTRLTDDISKISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFSDKELAAYAKAGAVAEEALSAIKTVIAFGGQNKELERYQRHLENAKKIGIKKAISANISMGIAFLLIYASYALAFWYGSTLVISKEYTIGNALTVFFSILIGAFSVGQAAPCIDSFAN | ||||||
Domain | 392-628 | ABC transporter | ||||
Sequence: LEFRNVHFSYPSRADVKILKGLNLKVNSGQTVALVGNSGCGKSTTVQLIQRLYDPLEGTINIDGQDIRTLNVRYLREIIGVVSQEPVLFATTIAENIRYGREDATMDEVKKAVKDANAYEFIMKLPEKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESESEVQAALDKAREGRTTIVIAHRLSTIRNADVIAGFEDGIITEQGSHNELMKKEGVYFKLVNM | ||||||
Domain | 711-998 | ABC transmembrane type-1 | ||||
Sequence: VVGTLCAIVNGALQPAFSIIFSEMLAIFGPGDDDVKQQKCNMFSLLFLGLGIISFFTFFLQGFTFGKAGEILTTRLRYMAFKAMLRQDMSWFDDPKNSTGALSTRLATDASQVQGATGSRLALIAQNTANLGTGIIISFVYGWQLTLLLLSVVPIIAVSGIIEIKMLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMYGENLNGPYRNSVRKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSAIVFGAMALGHASSFAPDYAK | ||||||
Domain | 1033-1271 | ABC transporter | ||||
Sequence: VSFNEVVFNYPTRPNVPVLQGLSLEVKKGHTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGQETKKLNVQWLRSQLGIVSQEPMLFDCSIAENIAYGNNSRVVSQEEIVNAAKAANIHPFIESLPEKYETRVGDKGTQLSGGQKQRIAIARALIRHPRILLLDEATSALDTESEKIVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGKVKEHGTHQQLLAQKGIYFSLVNV |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,278
- Mass (Da)140,921
- Last updated2010-08-10 v1
- Checksum48C362D0A80AF8D4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GU230140 EMBL· GenBank· DDBJ | ADI58770.1 EMBL· GenBank· DDBJ | mRNA |