D7GIX6 · D7GIX6_PROFC

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site37[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site38[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site103[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site132[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane respiratory chain complex I
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit B
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit B
    • NDH-1 subunit B

Gene names

    • Name
      nuoB
    • Ordered locus names
      PFREUD_05170

Organism names

Accessions

  • Primary accession
    D7GIX6

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain37-145NADH:ubiquinone oxidoreductase-like 20kDa subunit

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    20,311
  • Last updated
    2010-08-10 v1
  • Checksum
    45AE72FD45294C58
MGIEEKLPAGIFLTTVEQVQGWMRQASFWPLTMGLACCAIEMISYGGPRADCSRWGQEIFRASPRQADLMIVAGRVGQKLAPVVRQLWDQMPNPKWCIAMGACASSGGVFNNYAVVQGVDHIVPVDMYLPGCPPRPDMLIDAVFKLKKGKVQHTTMGAHRVQEVAELEQKALAAPATIEQKGLMR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FN806773
EMBL· GenBank· DDBJ
CBL56048.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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