D7GE78 · D7GE78_PROFC

Function

function

Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

Features

Showing features for binding site.

1827100200300400500600700800
TypeIDPosition(s)Description
Binding site486-493ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological Processcell division

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • DNA translocase FtsK

Gene names

    • Name
      ftsK
    • Ordered locus names
      PFREUD_13210

Organism names

Accessions

  • Primary accession
    D7GE78

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane94-112Helical
Transmembrane118-144Helical
Transmembrane212-231Helical

Keywords

Interaction

Subunit

Homohexamer. Forms a ring that surrounds DNA.

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-36Polar residues
Region1-53Disordered
Compositional bias272-286Basic and acidic residues
Region272-304Disordered
Domain468-669FtsK

Sequence similarities

Belongs to the FtsK/SpoIIIE/SftA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    827
  • Mass (Da)
    88,963
  • Last updated
    2010-08-10 v1
  • Checksum
    59F3FB82BA0FF6F0
MATRASSPSRPRSKSGSKNSRRPASARSGGSKKNNHSRGSASRRPRPTAPRPNPVLRAVVFAWQGIAHGLGAAVRRIGGSAREIDPAVRRDGMGLFLVALAVVVAAEFWVGLPGVVGQILQACVATIFGMASYLLPVLLFVLAWRTLRNPDSNGPVGRQALGWTVLAFGLLGLINVTEWPLPSPADPARMRAMGGIIGYISSSMLTQLVPRWLSAVLLVIVAVLGTILITGRPVHELWAQIRQLASGASSWAADNRAKKAERKLKFGVDEAYDTPVEDEDQHPASTEPHADPVAPRPDPAHPAAAVVAPDDLEPPEHLPATSRVEQLQLSGDVQYSLPELSLLKPGSAPKVHTDAADHTVNSLQDVFTEFNIDAQVTRYTRGPTVTQYEVELGSGVKVEKVTALQRNIAYAVASPDVRILSPIPGKSAIGIEIPNKEKEVVSLGDVLRSPRARSNTKPLVVGLGKDVEGRVVLANIAKMPHLLVAGATGSGKSSFVNSMITSIMLRATPDEVRMILVDPKRVELNQYEGIPHLVTPIITSPKKAAQALEWVVQEMDRRYDDLAAFGFRHIDDFNKAVRAGQVQLPPGSERELTPYPYLVVVVDELSDLMMVAPRDVEDSIVRITQLARAAGIHLVLATQRPSVDVVTGLIKANIPSRLAFATSSATDSRVILDQAGAERLLGQGDGLFLPMGAANPKRVQGSWVTEAEIREVVDHVKEQLKPQYRDDVTAVASAEKKVAEDIGDDLDLVLEAATNVVNLQLGSTSMLQRKLRIGFAKAGRIMDILETRGVVGPSEGSKPRDVYVKPDDLDTVLAQLSGEPQPESATQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-36Polar residues
Compositional bias272-286Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FN806773
EMBL· GenBank· DDBJ
CBL56839.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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