D6WQS9 · D6WQS9_TRICA

Function

Catalytic activity

  • [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine.
    EC:2.3.2.31 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentubiquitin ligase complex
Molecular Functionubiquitin conjugating enzyme binding
Molecular Functionubiquitin protein ligase activity
Molecular Functionzinc ion binding
Biological Processprotein polyubiquitination
Biological Processubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RBR-type E3 ubiquitin transferase
  • EC number

Gene names

    • Name
      AUGUSTUS-3.0.2_09974
    • ORF names
      TcasGA2_TC009974

Organism names

  • Taxonomic identifier
  • Strain
    • Georgia GA2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Tenebrionidae > Tenebrionidae incertae sedis > Tribolium

Accessions

  • Primary accession
    D6WQS9

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for repeat, domain, region, compositional bias.

Type
IDPosition(s)Description
Repeat45-78ANK
Repeat133-165ANK
Domain298-537RING-type
Domain302-351RING-type
Region801-820Disordered
Compositional bias804-820Polar residues
Region944-969Disordered
Region1162-1183Disordered
Compositional bias1237-1277Polar residues
Region1237-1302Disordered
Compositional bias1278-1296Basic and acidic residues
Region1326-1359Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,359
  • Mass (Da)
    152,959
  • Last updated
    2010-08-10 v1
  • MD5 Checksum
    18064FA22D1F3DC878F3FD52A28B0FE8
MGSTSSKFKKYLQHGDEFAAMQIYQSSPELRKNLDPNLSYGENHNHNTALHYAAKHGMKHLLRTFLNDLGGNPNKKNGLNESVLHSACQLNQTKSFSAQERRAACVQLLLYWKGGPLANGGRERVDLSSQDKEGNTALHWAASTGLKRCVELLLAHGAPLFIENNDKLTPCDLAMRGSHHDIARLLESRMVFADNADLVNEDEIITEQEEVYSGLRSQDLQEAKDQLLVDTSDMLKIPLFTAEALLRNNEWSRELLLEKWMKDPVECCQIAGVQAPSSVLKHAGSLESSISAETNDENEIMCEICLSTISNWEQPVKMSCKHSFCKTCWESYLTTKIQDGDAHHILCPAYQCHILVPVELIEKLVSPDMARRYLQFDIKAFVESNKSIKWCPIAGCGRAVRLPEAEQTGNRVNNKSAPITSHAVDCGNAHFFCWECLGEAHAPCGCKQWQEWQIKIAEIKPEELKASCSGSEDAANCLWLVTNSKPCPNCKSPIQKNEGCNHMKCSKCKFDFCWVCQESWKRHSSATGGYFRCNRFEAVHKADEKQGNLISEALDRNNQMQEMSRFLHFYTRFRNHENSQKLEEPLLTSVRQKREVLASSLGLKSTEDFGEKGTKFIEDGVRELLKARRVLCGSYVYGYYLEDDGYNKTIFEFMQNELEEVTEKLSEMIARPYLRTPKAVIVQTTALARRKRHEFVRAVAQGLIPPETPPSQRKRKRKYLDTDLTQTSAWLRDCEWPEYDSDEDNEVSFKQFSGGSPNSKEHQCGFLCSRHGCGRSDYNMELIIALEMSRLQMIEDRMKQAQANAITPDPSSSISNNSNESADDQLKLAIQLSLQESGAAEETVQSQPYQKSSADWTVDYFLKSLANHKIDLKSLDVNKLGTETDRELFFRPCNGNEDGRFQISDIHEKGFAFEDVDDYDDADVGLKRSHSTGDLCVRRSGRGTRVRMNGDEPRYHLDSDHSSQHDDKPEDLARKILALPSTSVRTKQFLLLHHTYPEEESYQGQSSIEDTTTSDSINADMEVCGILSSVTDEDIGKSYNEEEEIKKTEMTKIVECKKQTHNPFASLKAKLCSAHLPKTSYLTRIAVNKSIGLLSSDHKVKKNCDILKDDRCKSEKHSPKSIKHQKCCRGGSFSKSTGFLLEDQRKSCNLRIKICNSPDSKCRKGHTLETDSSNEYESETGIPKSPTLFISGVSISRTPEPKSPGMILIAGGRQSRSSSLSVPVPLTSCSLNISSTSLNNTLPPEPFTPSLVRSTTPANSRSNIPSPSNSSPKKEANAKSKSASEPEREREMFRFPKSSTDGALSSVLHIQESNLSSDDFHEALFLLERSPKTRDSKRRKKSKKNKEKDDKKEDVSSVL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias804-820Polar residues
Compositional bias1237-1277Polar residues
Compositional bias1278-1296Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KQ971354
EMBL· GenBank· DDBJ
EFA07004.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help