D6RJ31 · D6RJ31_MOUSE
- ProteinAlkaline ceramidase
- GeneAcer3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
Catalytic activity
- H2O + N-(9Z-octadecenoyl)-sphing-4-enine = (9Z)-octadecenoate + sphing-4-enineThis reaction proceeds in the forward direction.
- an N-acylsphinganine + H2O = a fatty acid + sphinganineThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism; sphingolipid metabolism.
Sphingolipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ceramidase activity | |
Molecular Function | N-acylsphingosine amidohydrolase activity | |
Biological Process | ceramide metabolic process | |
Biological Process | sphingosine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkaline ceramidase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionD6RJ31
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-52 | Helical | ||||
Sequence: FWNTVSNLIMIIPPIFGAI | ||||||
Transmembrane | 64-84 | Helical | ||||
Sequence: IAAYLALTVVGMGSWCFHMTL |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length90
- Mass (Da)10,340
- Last updated2010-07-13 v1
- ChecksumC6C3DC39FD2C236C
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Keywords
- Technical term