D6RJ31 · D6RJ31_MOUSE

  • Protein
    Alkaline ceramidase
  • Gene
    Acer3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Lipid metabolism; sphingolipid metabolism.
Sphingolipid metabolism.

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionceramidase activity
Molecular FunctionN-acylsphingosine amidohydrolase activity
Biological Processceramide metabolic process
Biological Processsphingosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkaline ceramidase
  • EC number

Gene names

    • Name
      Acer3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    D6RJ31

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane34-52Helical
Transmembrane64-84Helical

Keywords

  • Cellular component

Expression

Gene expression databases

Structure

Family & Domains

Sequence similarities

Belongs to the alkaline ceramidase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    90
  • Mass (Da)
    10,340
  • Last updated
    2010-07-13 v1
  • Checksum
    C6C3DC39FD2C236C
MAPAVDRKGYWGPTTSTLDWCEENYVVTLFVAEFWNTVSNLIMIIPPIFGAIQGIRDRLEKRYIAAYLALTVVGMGSWCFHMTLKYEMQV

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9D099ACER3_MOUSEAcer3267
F6RA04F6RA04_MOUSEAcer3174
D3YTU8D3YTU8_MOUSEAcer3225

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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